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Filtrado por: Contribuyente GlaxoSmithKline Departamento, Escuela o Facultad Strathclyde Institute of Pharmacy and Biomedical Sciences Tipo Thesis

Investigating streptomyces clavuligerus linear replicons for improved clavulanic acid production

Creador:

Mohit, Elmira

Fecha:

2023 and 2024

Funder:

Biotechnology and Biological Sciences Research Council, GlaxoSmithKline, and Industrial Biotechnology Innovation Centre

Department, School or Faculty:

Strathclyde Institute of Pharmacy and Biomedical Sciences
Early application of mechanistic PKPD modelling to guide the preclinical development of a therapeutic mAb targeting complement receptor 2 (CR2/CD21) as a novel target for the treatment of autoimmune disease

Creador:

Hooper-Greenhill, Edward

Fecha:

2021

Funder:

GlaxoSmithKline

Department, School or Faculty:

Strathclyde Institute of Pharmacy and Biomedical Sciences
Understanding the hepatic disposition of statins to improve predictions of safety and efficacy

Creador:

Heslop, Teresa Louise

Fecha:

2019

Funder:

GlaxoSmithKline

Department, School or Faculty:

Strathclyde Institute of Pharmacy and Biomedical Sciences
Pharmacological characterisation of small molecule RGD-mimetics targeting αvβ6-mediated activation of TGFβ in idiopathic pulmonary fibrosis

Creador:

Slack, Robert J.

Fecha:

2015

Funder:

GlaxoSmithKline

Department, School or Faculty:

Strathclyde Institute of Pharmacy and Biomedical Sciences
New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities

Creador:

Teague, Simon Peter

Fecha:

2019

Funder:

GlaxoSmithKline

Department, School or Faculty:

Strathclyde Institute of Pharmacy and Biomedical Sciences
Development towards prospective modelling of in vivo rabbit QTc prolongation

Creador:

Lewis, Gareth John

Fecha:

2017

Funder:

GlaxoSmithKline

Department, School or Faculty:

Strathclyde Institute of Pharmacy and Biomedical Sciences

Investigating streptomyces clavuligerus linear replicons for improved clavulanic acid production

Early application of mechanistic PKPD modelling to guide the preclinical development of a therapeutic mAb targeting complement receptor 2 (CR2/CD21) as a novel target for the treatment of autoimmune disease

Understanding the hepatic disposition of statins to improve predictions of safety and efficacy

Pharmacological characterisation of small molecule RGD-mimetics targeting αvβ6-mediated activation of TGFβ in idiopathic pulmonary fibrosis

New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities

Development towards prospective modelling of in vivo rabbit QTc prolongation

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