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Catalytic methods for etherification reactions
1 di 20
Investigating streptomyces clavuligerus linear replicons for improved clavulanic acid production
2 di 20
Synthetic approaches to heterocyclic systems of pharmaceutical relevance
3 di 20
Early application of mechanistic PKPD modelling to guide the preclinical development of a therapeutic mAb targeting complement receptor 2 (CR2/CD21) as a novel target for the treatment of autoimmune disease
4 di 20
Homogeneous hydrogenation and photochemistry as tools in pharmaceutical process development
5 di 20
Development of lysine acylating small molecules for covalent kinase inhibition
6 di 20
Novel heterocyclic ligands for the lipid kinase PI4KIIIβ : a chemical biology approach
7 di 20
A medicinal chemistry approach towards brodomain epigenetic modulators
8 di 20
Synthesis and optimisation of novel molecules to probe epigenetic mechanisms with applications in the treatment of inflammatory disorders
9 di 20
The development and evaluation of a method for the quantitative determination of a monoclonal antibody using capillary electrophoresis-high resolution mass spectrometry
10 di 20
The use of structure-based drug design to optimise protein-ligand interactions
11 di 20
The design, synthesis and optimisation of αvβ6 antagonists as potential idiopathic pulmonary fibrosis agents
12 di 20
Electrochemically enabled synthesis of substituted isoxazolines
13 di 20
αV integrin antagonists for the treatment of idiopathic pulmonary fibrosis
14 di 20
Application of electrochemical based sensors in support of toxicokinetic and pharmacokinetics
15 di 20
Development of photoaffinity labelling technologies for small molecule drug discovery - a case study targeting bromodomains
16 di 20
New methods for the synthesis of pharmaceutical azacycles
17 di 20
New hydrogen atom transfer methodologies for synthesis
18 di 20
Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
19 di 20
Hi-JAK-ing the ubiquitin system : the design and physicochemical optimisation of JAK PROTACs
20 di 20