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The design and synthesis of targeted BET inhibitors
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Novel C-C bond formation strategies for access to secondary and tertiary amides enabled by new synthetic technologies
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Design and synthesis of dimethylisoxazole quinolines as BET inhibitors
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Targeted protein degradation as a new approach to drug discovery
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Use of fragment-based drug discovery to identify novel drug molecules for challenging biological targets, including protein-protein interactions
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The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
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Novel applications of magnesium base systems in preparative organic chemistry and asymmetric synthesis
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Iridium(I) complexes for the functionalisation of carbon-hydrogen bonds
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Computationally guided rational ligand design of novel iridium (I) complexes for elevated substrate applicability in hydrogen isotope exchange processes
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Design and development of halodeboronation methods for organic synthesis
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