Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
1 of 8
The design and synthesis of chemical probes for non-BET bromodomains
2 of 8
New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
3 of 8
New chemical approaches for the development of targeted protein degradation
4 of 8
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
5 of 8
The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
6 of 8
Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters