Early application of mechanistic PKPD modelling to guide the preclinical development of a therapeutic mAb targeting complement receptor 2 (CR2/CD21) as a novel target for the treatment of autoimmune disease

Understanding the hepatic disposition of statins to improve predictions of safety and efficacy

Pharmacological characterisation of small molecule RGD-mimetics targeting αvβ6-mediated activation of TGFβ in idiopathic pulmonary fibrosis

New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities

Development towards prospective modelling of in vivo rabbit QTc prolongation