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日期
2019
删除限定条件 日期: 2019
出资者
GlaxoSmithKline
删除限定条件 出资者: GlaxoSmithKline
类型
Thesis
删除限定条件 类型: Thesis
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Development and understanding of rhodium-catalysed conjugate arylation for process chemistry applications
1 of 10
Synthesis and biological evaluation of novel small molecule bromodomain inhibitors
2 of 10
Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
3 of 10
The design and synthesis of chemical probes for non-BET bromodomains
4 of 10
New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
5 of 10
New chemical approaches for the development of targeted protein degradation
6 of 10
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
7 of 10
The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
8 of 10
Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
9 of 10
Automated, quantitative process analysis by NMR
10 of 10