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Evaluating the application and limitations of bio-based solvents within organic synthesis
1 di 20
The design and synthesis of molecular tools for probing biological function
2 di 20
Investigations into the generation and pleiotropic reactivity modes of the nitrile imine 1,3-dipole
3 di 20
Development of novel allosteric regulators of proteinase-activated receptors
4 di 20
Approaches to lead generation for idiopathic pulmonary fibrosis targets
5 di 20
Structure-guided approaches to the design of novel autotaxin inhibitors
6 di 20
Application of computer vision in industrially important reactions
7 di 20
Application of bioisosteres to modulate molecular properties in medicinal chemistry
8 di 20
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
9 di 20
The use of contemporary chemoproteomic techniques in antimalarial target identification
10 di 20
The synthesis and optimisation of toll-like receptor agonists as potential immunomodulatory agents
11 di 20
The design, synthesis and optimisation of calcium release-activated calcium (CRAC) channel inhibitors and mitochondrial permeability transition pore (mPTP) modulators, using phenotypic screening
12 di 20
Studies towards the synthesis and labelling of bioactive peptides
13 di 20
Novel approaches targeting phosphoinositide 3-kinase delta
14 di 20
The development of small molecule inhibitors for fibrosis drug discovery
15 di 20
The development of natural products as phytotoxic leads for herbicide discovery
16 di 20
New methods for the construction of selectively difluorinated carbocycles
17 di 20
The development of novel organocatalytic and transition-metal catalysed methodologies for amide bond formation
18 di 20
Computer-aided drug design of bicyclic-derived BRD4 inhibitors
19 di 20
Investigation of LPA₁ receptor antagonism / ATX inhibition by a scaffold hopping aproach and SAR analysis
20 di 20