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Development of new chemical tools as crop protecting agents
1 di 25
Synthetic approaches to heterocyclic systems of pharmaceutical relevance
2 di 25
Expedient access to C-aryl linked saturated heterocyclic motifs
3 di 25
Homogeneous hydrogenation and photochemistry as tools in pharmaceutical process development
4 di 25
The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
5 di 25
Investigation of LPA₁ receptor antagonism / ATX inhibition by a scaffold hopping aproach and SAR analysis
6 di 25
Computer-aided drug design of bicyclic-derived BRD4 inhibitors
7 di 25
The development of novel organocatalytic and transition-metal catalysed methodologies for amide bond formation
8 di 25
New methods for the construction of selectively difluorinated carbocycles
9 di 25
The development of natural products as phytotoxic leads for herbicide discovery
10 di 25
The development of small molecule inhibitors for fibrosis drug discovery
11 di 25
Novel approaches targeting phosphoinositide 3-kinase delta
12 di 25
Studies towards the synthesis and labelling of bioactive peptides
13 di 25
The design, synthesis and optimisation of calcium release-activated calcium (CRAC) channel inhibitors and mitochondrial permeability transition pore (mPTP) modulators, using phenotypic screening
14 di 25
The synthesis and optimisation of toll-like receptor agonists as potential immunomodulatory agents
15 di 25
The use of contemporary chemoproteomic techniques in antimalarial target identification
16 di 25
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
17 di 25
Application of bioisosteres to modulate molecular properties in medicinal chemistry
18 di 25
Application of computer vision in industrially important reactions
19 di 25
Structure-guided approaches to the design of novel autotaxin inhibitors
20 di 25
Approaches to lead generation for idiopathic pulmonary fibrosis targets
21 di 25
Development of novel allosteric regulators of proteinase-activated receptors
22 di 25
Investigations into the generation and pleiotropic reactivity modes of the nitrile imine 1,3-dipole
23 di 25
The design and synthesis of molecular tools for probing biological function
24 di 25
Evaluating the application and limitations of bio-based solvents within organic synthesis
25 di 25