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Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
Creador:
Summers, Declan M.
Fecha:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
Creador:
Baker, Blake Jamie Mark
Fecha:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Iron-catalysed cross-couplings of secondary alkyl Grignard reagents
Creador:
Sanderson, James
Fecha:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Computational modelling of enzyme activity to speed up biocatalyst redesign
Creador:
Dréanic, Marie-Pierre
Fecha:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Increasing the saturation of BET inhibitors
Creador:
Dixon, Joseph Edward
Fecha:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
Creador:
Wood, Susanna Helen
Fecha:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of small molecules for treatment of idiopathic pulmonary fibrosis (IPF)
Creador:
Campbell-Crawford, Matthew H. J.
Fecha:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of small molecule bromodomain inhibitors
Creador:
Lucas, Simon Christopher Cranko Alcock
Fecha:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Pharmacological characterisation of the 5-HT receptors present on mouse and human hepatic stellate cells and their role in liver fibrosis
Creador:
Barrett, Victoria J.
Fecha:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Investigating and exploiting best practices in hit identification and hit to lead chemistry
Creador:
Borthwick, Jennifer
Fecha:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
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