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GlaxoSmithKline
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Development of novel inhibitors of carbohydrate-processing targets involved in Mycobacterium tuberculosis cell wall biosynthesis
创造者:
Whitehurst, Ben.
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The synthesis & optimisation of irreversible ITK inhibitors as a potential new treatment for severe asthma
创造者:
Campos, Sébastien André.
日期:
2013
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Automated, quantitative process analysis by NMR
创造者:
Watson, Simon Andrew.
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Pharmacological characterisation of the 5-HT receptors present on mouse and human hepatic stellate cells and their role in liver fibrosis
创造者:
Barrett, Victoria J.
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
创造者:
Wood, Susanna Helen
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Effects of OGG1 activation on mitochondrial function in response to oxidative stress
创造者:
Katchur, Steven R.
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences.
New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
创造者:
Teague, Simon Peter
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Development of small molecule splice-switchers as inducers of apoptosis
创造者:
Campbell, Emma
日期:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Approaches to lead generation for idiopathic pulmonary fibrosis targets
创造者:
Duffy, Emma.
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
New route investigation and process development in the synthesis of GSK221149
创造者:
Roberts, Alastair
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of targeted BET inhibitors
创造者:
Robertson, Craig Michael
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development towards prospective modelling of in vivo rabbit QTc prolongation
创造者:
Lewis, Gareth John
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Studies and improvement of molecular docking methods in rigid and flexible receptors
创造者:
Le Gall, Armelle
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Development of the C-methyltransferases NovO and CouO for biocatalytic Friedel-Crafts alkylation
创造者:
Sadler, Joanna C.
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Structure-guided approaches to the design of novel autotaxin inhibitors
创造者:
Potjewyd, Frances
日期:
2016
Funder:
Engineering and Physical Sciences Research Council
and
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of photoaffinity labelling technologies for small molecule drug discovery - a case study targeting bromodomains
创造者:
Fallon, David
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of electrochemical based sensors in support of toxicokinetic and pharmacokinetics
创造者:
Mahammed, Farjana
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
创造者:
Baker, Blake Jamie Mark
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of bioisosteres to modulate molecular properties in medicinal chemistry
创造者:
Measom, Nicholas
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of chemical probes for non-BET bromodomains
创造者:
Clegg, Michael A.
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of chemical probes for non-BET bromodomains
创造者:
Theodoulou, Natalie
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Use of fragment-based drug discovery to identify novel drug molecules for challenging biological targets, including protein-protein interactions
创造者:
White, Gemma Victoria
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
创造者:
Summers, Declan M.
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of small molecules for treatment of idiopathic pulmonary fibrosis (IPF)
创造者:
Campbell-Crawford, Matthew H. J.
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of epigenetic mechanism inhibitors
创造者:
Campbell, Matthew.
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Sustainable cross-couplings for pharmaceutical scale-up using aryldiazonium salts
创造者:
Colleville, Aymeric Pierre.
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The design, synthesis and optimisation of kinase inhibitors as potential anti-inflammatory agents
创造者:
Harrison, Zoë A.
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
New hydrogen atom transfer methodologies for synthesis
创造者:
Turner, Oliver
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigations of the synthesis and properties of romodomain and extra-terminal domain proteolysis targeting chimeras
创造者:
Priestner, John C.
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The use of contemporary chemoproteomic techniques in antimalarial target identification
创造者:
Tucker, Jessie S.
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Preclinical development of a treatment for systemic lupus erythematosus
创造者:
Murray, Erin
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of novel epigenetic modulators
创造者:
Jones, Katherine
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Design and synthesis of dimethylisoxazole quinolines as BET inhibitors
创造者:
Wellaway, Christopher Roland
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of chemo- and regioselective reactions of boron systems
创造者:
Clohessy, Thomas A.
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New chemical approaches for the development of targeted protein degradation
创造者:
Lithgow, Hannah
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Targeted protein degradation as a new approach to drug discovery
创造者:
Tinworth, Christopher Patrick
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of probe molecules to validate the inhibition of epigenetic mechanisms for phenotypic responses
创造者:
Hayhow, Thomas G.
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The synthesis and optimisation of toll-like receptor agonists as potential immunomodulatory agents
创造者:
Tape, Daniel Terence.
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The design, synthesis and optimisation of phosphoinositide-3-kinase (PI3K) inhibitors as potential anti-inflammatory agents
创造者:
Hardy, Charlotte.
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The design, synthesis and optimisation of calcium release-activated calcium (CRAC) channel inhibitors and mitochondrial permeability transition pore (mPTP) modulators, using phenotypic screening
创造者:
Lacroix, Yannick
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Hi-JAK-ing the ubiquitin system : the design and physicochemical optimisation of JAK PROTACs
创造者:
Shah, Rishi R.
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New methods for the synthesis of pharmaceutical azacycles
创造者:
Clark, Peter
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
创造者:
Heslop, Teresa Louise
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
The development and evaluation of a method for the quantitative determination of a monoclonal antibody using capillary electrophoresis-high resolution mass spectrometry
创造者:
Snell, Richard
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
A medicinal chemistry approach towards brodomain epigenetic modulators
创造者:
Law, Robert Peter
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis and optimisation of novel molecules to probe epigenetic mechanisms with applications in the treatment of inflammatory disorders
创造者:
Diallo, Hawa
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel C-C bond formation strategies for access to secondary and tertiary amides enabled by new synthetic technologies
创造者:
Williams, Jason D.
日期:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies towards the synthesis and labelling of bioactive peptides
创造者:
Stewart, Sam
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel approaches targeting phosphoinositide 3-kinase delta
创造者:
Spencer, Jonathan Andrew
日期:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Iron-catalysed cross-couplings of secondary alkyl Grignard reagents
创造者:
Sanderson, James
日期:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
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76
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创造者
Anderson, Niall A.
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Baker, Blake Jamie Mark
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Barham, Joshua Philip
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Barrett, Victoria J.
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Bertrand, Sophie
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Jamieson, Craig
14
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GlaxoSmithKline
81
Biotechnology and Biological Sciences Research Council
1
Carnegie Trust for the Universities of Scotland
1
EPSRC Centre for Doctoral Training in Technology Enhanced Chemical Synthesis
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Department of Pure and Applied Chemistry
53
Department of Pure and Applied Chemistry.
20
Strathclyde Institute of Pharmacy and Biomedical Sciences
6
Strathclyde Institute of Pharmacy and Biomedical Sciences.
2
WestCHEM.
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