Ricerca
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Collaboratore
GlaxoSmithKline
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Data
2019
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genere
Thesis
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Development and understanding of rhodium-catalysed conjugate arylation for process chemistry applications
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Synthesis and biological evaluation of novel small molecule bromodomain inhibitors
2 di 10
Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
3 di 10
The design and synthesis of chemical probes for non-BET bromodomains
4 di 10
New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
5 di 10
New chemical approaches for the development of targeted protein degradation
6 di 10
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
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The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
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Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
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Automated, quantitative process analysis by NMR
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