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贡献者
GlaxoSmithKline
删除限定条件 贡献者: GlaxoSmithKline
日期
2016
删除限定条件 日期: 2016
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A medicinal chemistry approach towards brodomain epigenetic modulators
1 of 18
The design and synthesis of targeted BET inhibitors
2 of 18
Development of chemical probes for non-BET bromodomains
3 of 18
Novel PI3Kδ inhibitors for the treatment of inflammatory diseases
4 of 18
Use of fragment-based drug discovery to identify novel drug molecules for challenging biological targets, including protein-protein interactions
5 of 18
Studies towards the synthesis and labelling of bioactive peptides
6 of 18
Investigating and exploiting best practices in hit identification and hit to lead chemistry
7 of 18
Structure-guided approaches to the design of novel autotaxin inhibitors
8 of 18
The synthesis and optimisation of toll-like receptor agonists as potential immunomodulatory agents
9 of 18
Sustainable cross-couplings for pharmaceutical scale-up using aryldiazonium salts
10 of 18
The design, synthesis and optimisation of phosphoinositide-3-kinase (PI3K) inhibitors as potential anti-inflammatory agents
11 of 18
The interplay of multiple ADME mechanisms : prediction of hepatic drug-drug interactions from in vitro
12 of 18
Approaches to lead generation for idiopathic pulmonary fibrosis targets
13 of 18
The design, synthesis and optimisation of epigenetic mechanism inhibitors
14 of 18
Utilisation of rearrangement chemistry in the synthesis of novel fluorinated ring systems : a computational and experimental study
15 of 18
The development of small molecule inhibitors for fibrosis drug discovery
16 of 18
Development of novel inhibitors of carbohydrate-processing targets involved in Mycobacterium tuberculosis cell wall biosynthesis
17 of 18
Effects of OGG1 activation on mitochondrial function in response to oxidative stress
18 of 18
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类型
Thesis
18
资源类型
Doctoral thesis
18
创造者
Borthwick, Jennifer
1
Campbell, Matthew
1
Colleville, Aymeric Pierre
1
Duffy, Emma
1
Hardy, Charlotte
1
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创造者s
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贡献者
GlaxoSmithKline
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18
Jamieson, Craig
5
Watson, Allan
4
Kerr, William
2
Tomkinson, Nick
2
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贡献者s
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出资者
GlaxoSmithKline
18
Engineering and Physical Sciences Research Council
1
部门,学校或学院
Department of Pure and Applied Chemistry
17
Strathclyde Institute of Pharmacy and Biomedical Sciences
1
日期
2016
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18