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New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
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Development towards prospective modelling of in vivo rabbit QTc prolongation
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Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
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Early application of mechanistic PKPD modelling to guide the preclinical development of a therapeutic mAb targeting complement receptor 2 (CR2/CD21) as a novel target for the treatment of autoimmune disease
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Pharmacological characterisation of small molecule RGD-mimetics targeting αvβ6-mediated activation of TGFβ in idiopathic pulmonary fibrosis
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Investigating streptomyces clavuligerus linear replicons for improved clavulanic acid production
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