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Risultati della ricerca
Synthetic approaches to heterocyclic systems of pharmaceutical relevance
Creatore:
Green, Luke
Data:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Catalytic methods for etherification reactions
Creatore:
Whitaker, Luke
Data:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigating streptomyces clavuligerus linear replicons for improved clavulanic acid production
Creatore:
Mohit, Elmira
Data:
2023 and 2024
Funder:
Biotechnology and Biological Sciences Research Council
,
GlaxoSmithKline
, and
Industrial Biotechnology Innovation Centre
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
The design and synthesis of small molecule bromodomain inhibitors
Creatore:
Lucas, Simon Christopher Cranko Alcock
Data:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Homogeneous hydrogenation and photochemistry as tools in pharmaceutical process development
Creatore:
Shaalan, Youssef
Data:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
Creatore:
Tame, Christopher J.
Data:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel PI3Kδ inhibitors for the treatment of inflammatory diseases
Creatore:
Taylor, Jonathan Andrew
Data:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Chemoselective C-H functionalisation of aliphatic azacycles : utilisation of electrophilic iodine as a mild oxidant
Creatore:
Griffiths, Robert Joseph
Data:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel heterocyclic ligands for the lipid kinase PI4KIIIβ : a chemical biology approach
Creatore:
Cosgrove, Brett
Data:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Electrochemically enabled synthesis of substituted isoxazolines
Creatore:
Holman, Samuel David Lee
Data:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of lysine-targeted irreversible inhibitors of PI3Kδ
Creatore:
Dalton, Samuel E.
Data:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of αvβ6 antagonists as potential idiopathic pulmonary fibrosis agents
Creatore:
Anderson, Niall A.
Data:
2013
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
αV integrin antagonists for the treatment of idiopathic pulmonary fibrosis
Creatore:
Thompson, James
Data:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of CCR4 antagonists for the treatment of asthma
Creatore:
Miah, Afjal Hussain
Data:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The use of structure-based drug design to optimise protein-ligand interactions
Creatore:
Bertrand, Sophie
Data:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Pharmacological characterisation of small molecule RGD-mimetics targeting αvβ6-mediated activation of TGFβ in idiopathic pulmonary fibrosis
Creatore:
Slack, Robert J.
Data:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Early application of mechanistic PKPD modelling to guide the preclinical development of a therapeutic mAb targeting complement receptor 2 (CR2/CD21) as a novel target for the treatment of autoimmune disease
Creatore:
Hooper-Greenhill, Edward
Data:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
The interplay of multiple ADME mechanisms : prediction of hepatic drug-drug interactions from in vitro
Creatore:
Hobbs, Michael.
Data:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
New treatments for inflammatory diseases : optimisation and understanding of key processes
Creatore:
Davies, Suzanne H.
Data:
2012
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry. and WestCHEM.
Utilisation of rearrangement chemistry in the synthesis of novel fluorinated ring systems : a computational and experimental study
Creatore:
Orr, David George Alexander.
Data:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
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Strathclyde Institute of Pharmacy and Biomedical Sciences.
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