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GlaxoSmithKline
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Structure-guided approaches to the design of novel autotaxin inhibitors
1 of 20
The synthesis and optimisation of toll-like receptor agonists as potential immunomodulatory agents
2 of 20
Sustainable cross-couplings for pharmaceutical scale-up using aryldiazonium salts
3 of 20
The design, synthesis and optimisation of phosphoinositide-3-kinase (PI3K) inhibitors as potential anti-inflammatory agents
4 of 20
The interplay of multiple ADME mechanisms : prediction of hepatic drug-drug interactions from in vitro
5 of 20
Single electron transfer in organic synthesis targeted towards sustainable manufacture
6 of 20
The design, synthesis and optimisation of CCR4 antagonists for the treatment of asthma
7 of 20
Approaches to lead generation for idiopathic pulmonary fibrosis targets
8 of 20
New methods for the construction of selectively difluorinated carbocycles
9 of 20
Automated, quantitative process analysis by NMR
10 of 20
The design, synthesis and optimisation of epigenetic mechanism inhibitors
11 of 20
Utilisation of rearrangement chemistry in the synthesis of novel fluorinated ring systems : a computational and experimental study
12 of 20
The synthesis & optimisation of irreversible ITK inhibitors as a potential new treatment for severe asthma
13 of 20
New treatments for inflammatory diseases : optimisation and understanding of key processes
14 of 20
The development of small molecule inhibitors for fibrosis drug discovery
15 of 20
Development of novel inhibitors of carbohydrate-processing targets involved in Mycobacterium tuberculosis cell wall biosynthesis
16 of 20
Effects of OGG1 activation on mitochondrial function in response to oxidative stress
17 of 20
Mechanistic pharmacokinetic / pharmacodynamic modelling of acute inflammatory challenge models
18 of 20
Studies and improvement of molecular docking methods in rigid and flexible receptors
19 of 20
The design, synthesis and optimisation of kinase inhibitors as potential anti-inflammatory agents
20 of 20
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类型
Thesis
81
资源类型
Doctoral thesis
76
Master thesis
5
创造者
Anderson, Niall A.
1
Baker, Blake Jamie Mark
1
Barham, Joshua Philip
1
Barrett, Victoria J.
1
Bertrand, Sophie
1
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贡献者
GlaxoSmithKline
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81
Jamieson, Craig
14
Kerr, William
6
Tomkinson, Nicholas
6
Watson, Allan
6
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出资者
GlaxoSmithKline
81
Biotechnology and Biological Sciences Research Council
1
Carnegie Trust for the Universities of Scotland
1
EPSRC Centre for Doctoral Training in Technology Enhanced Chemical Synthesis
1
Engineering and Physical Sciences Research Council
1
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部门,学校或学院
Department of Pure and Applied Chemistry
53
Department of Pure and Applied Chemistry.
20
Strathclyde Institute of Pharmacy and Biomedical Sciences
6
Strathclyde Institute of Pharmacy and Biomedical Sciences.
2
WestCHEM.
1
日期
2016
18
2020
12
2018
11
2017
9
2019
8
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