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Synthetic approaches to heterocyclic systems of pharmaceutical relevance
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Homogeneous hydrogenation and photochemistry as tools in pharmaceutical process development
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Application of bioisosteres to modulate molecular properties in medicinal chemistry
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The use of contemporary chemoproteomic techniques in antimalarial target identification
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Novel approaches targeting phosphoinositide 3-kinase delta
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The design, synthesis and optimisation of calcium release-activated calcium (CRAC) channel inhibitors and mitochondrial permeability transition pore (mPTP) modulators, using phenotypic screening
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The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
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Studies towards the synthesis and labelling of bioactive peptides
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Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
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Structure-guided approaches to the design of novel autotaxin inhibitors
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