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Department of Pure and Applied Chemistry
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Developing electrochemical methods for monitoring of therapeutic drugs
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Developing a click chemistry imaging platform using aromatic ynamines.
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Design & synthesis of antimicrobial minor groove binders
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Mechanistic and computational investigations into the copper(I)-catalysed sulfonylative cross couplings of sulfur dioxide and related sulfinate intermediates
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The development of BET BD1 selective chemical probes
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Assessment of urban airborne potentially toxic elements using bioindicator plants
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Probing protein-protein interactions by HDX-MS and computational approaches
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Novel reactive fragment screening technologies
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Visible-light-mediated annulations and rearrangements for the amination of electron-rich aromatics
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New iridium catalysed methods for enantioselective imine hydrogenation
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Isolation and characterisation of small extracellular vesicles from the human pancreatic cancer cell line BxPC-3.
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Synthesis and catalytic applications of new heavy s-block metal amides
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Comparative forensic examination of fibres and gunshot-residue by vibrational spectroscopy and machine learning
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Single electron transfer reactions mediated by photoredox catalysis or potassium metal
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Investigations of s-block organoelement (nitrogen, oxygen) chemistry
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Beyond traditional peptide design : exploring peptoid and aliphatic molecular assembly
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The application of active learning to the lead optimisation of a novel series of antimalarials
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Development and understanding of rhodium-catalysed conjugate arylation for process chemistry applications
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Expanding the scope of asymmetric redox-relay oxidative Heck transformations
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Development of voltammetric screening approaches for synthetic cannabinoids
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Synthetic approaches to tune gas sorption properties in new lantern-type metal-organic polyhedral
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A study of the electrophilic and radicophilic activation of certain classes of amines
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Potentially toxic elements in soils impacted by crude oil production and historical lead mining
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Exploiting DNA-encoded library : technology for the discovery of novel antibody recruiting molecules against LOX-1
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Detection of galectin proteins using advanced raman rechniques
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Visible light harvesting nanocomposite heterojunction photocatalysts for remediating crude oil contaminated water
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Application of ATR-FTIR spectroscopy for the direct detection of stimulants in biofluids
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Synthesis and biological evaluation of novel small molecule bromodomain inhibitors
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Polymer-supported components as lubricant additives
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The role of chemometrics and machine learning in cancer diagnostics
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The development and evaluation of multifunctional silver iron-oxide hybrid nanoparticles towards enhanced pancreatic cancer therapy
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Perovskite solar cells for indoor light harvesting
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Development of functionalised nanoparticles for cancer imaging using Surface-Enhanced Spatially Offset Raman Spectroscopy (SESORS)
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Development of Perovskite solar cells on ultrathin deformable substrates
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Synthesis and characterisation of crosslinked polymer resins derived from epoxidised natural rubber latex
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Developments in surface-enhanced spatially offset Raman spectroscopy for through-tissue imaging applications
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Development of new synthetic approaches in solid-phase peptide synthesis
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Polymer self-assemblies : microfluidic production and nucleobase-functionalities
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Functionalised gelatin for vascular graft sealant applications
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Synthesis and evaluation of organic/inorganic hybrid materials for high temperature applications
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Iridium-catalysed hydrogen isotope exchange of n-heterocycles and nucleosides
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Effect of fertilisers on the availability of potentially toxic elements in soil
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Routes towards reducing hazards in industrial coatings
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Catalytic methods for etherification reactions
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Electrochemical supercapacitors from upcycled biomass and plastic waste derived activated carbon composites
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Next-generation transcriptional activators for the treatment of Friedreich’s Ataxia
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Magnetically enhanced sensing: advancements in SERS-active magnetic particle development
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Peptoids : targeting sequence specific high molecular weight materials for protein mimetic applications
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Computer-aided drug design of bicyclic-derived BRD4 inhibitors
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New developments in main group chemistry for application in modern battery technology
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Cancer phototherapy with precisely defined and highly functionalized phthalocyanine photosensitizers
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Investigation of the detection and quantification of nanomaterials in biomatrices for cancer research applications
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Raman spectroscopy for the investigation of gold nanoparticles in Glioblastoma
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Synthetic approaches to heterocyclic systems of pharmaceutical relevance
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SERS in the second biological window: towards in-vivo applications
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Force field development and molecular dynamics simulations of triacylglycerides
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Sulfur chemistry : thiolates, disulfides, thioethers and thiones
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Studies toward the development of novel coupling reactions
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Physics-based and deep learning approaches for the determination of solution thermodynamic parameters
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Structure activity studies of aminoindole anti-malarial agents to enhance physicochemical properties and safety profile
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Studies in Raman, infrared and acoustic emission spectrometries and reaction calorimetry for process analysis
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Potentially heptadentate ligands in the synthesis of redox active compounds
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Understanding spectral signatures of cancerous disease states
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Investigating the host defence peptide, LL-37, as an antimicrobial : a Raman microscopic approach
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Process analytical technologies for particle characterisation and solid form analysis in continuous secondary pharmaceutical manufacturing
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A test to identify mammalian species present in forensic trace samples and mixtures using the mitochondrial cytochrome b gene
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Homoleptic crown carbenes
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New iridium-catalysed methods for the hydrogen isotope exchange of pharmaceutically-relevant compounds
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Investigation into novel antibacterial agents that will bind at GyrA/ParC or GyrB/ParE subunits of DNA gyrase/topoimerase IV
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Synthesis and characterisation of homometallic (Mg) and heterobimetallic (Na/Mg, K/Mg, K/Zn, Li/Al, Na/Al, K/Al) compounds with alkoxo, alkyl, amido or halo ligands
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New synthetic and structural alkali metal chemistry of alkoxide and triazine ligands
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Copper complexes as putative imaging agents
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Novel synthesis of carbon-carbon mainchain optically active polymers
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Homogeneous hydrogenation and photochemistry as tools in pharmaceutical process development
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Extending peptide search space and self-assembly methods
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Development of lysine acylating small molecules for covalent kinase inhibition
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Novel heterocyclic ligands for the lipid kinase PI4KIIIβ : a chemical biology approach
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Studies on the photodegradation of polyurethane foam
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Bioinspired amphipilic polymer conetworks
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Advances in the synthesis and application of iridium (I) complexes for use in hydrogen isotope exchange
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Development of novel synthetic and analytic protocols for cationic magnesium complexes relevant to battery applications
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Elucidation of complex reaction mechanisms through the application of density functional theory
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A medicinal chemistry approach towards brodomain epigenetic modulators
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Multipurpose polymer wafers for skin regeneration
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Adhesive formulations for lens applications
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Synthesis and optimisation of novel molecules to probe epigenetic mechanisms with applications in the treatment of inflammatory disorders
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The solid-state structure of tricyclic antidepressants
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Development and study of donor-acceptor Stenhouse adduct junction-functionalised block copolymers
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Human bioaccessibility of potentially toxic elements in soils using three in-vitro extraction methods
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Novel methods to access tracelessly labelled molecules via iridium-catalysed hydrogen isotope exchange
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The search for radicals in unexpected places
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The development and evaluation of a method for the quantitative determination of a monoclonal antibody using capillary electrophoresis-high resolution mass spectrometry
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Synthesis enabled drug discovery
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Investigating novel reagents in organic synthesis
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Physicochemical studies on spectroscopic characterization, preconcentration, separation, determination and/or chemical speciation of various inorganic and organic complex species in different media
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The use of structure-based drug design to optimise protein-ligand interactions
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The design, synthesis and optimisation of αvβ6 antagonists as potential idiopathic pulmonary fibrosis agents
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Electrochemically enabled synthesis of substituted isoxazolines
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αV integrin antagonists for the treatment of idiopathic pulmonary fibrosis
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Application of electrochemical based sensors in support of toxicokinetic and pharmacokinetics
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