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Characterisation of novel compounds as antagonists of protease-activated receptor-2 (PAR2)
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Measurements in optical microscopy
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Applications of hydrophilic interation chromatography in the analysis of drugs and metabolites
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Control of human inflammatory cell responses by prostaglandins and related metabolites
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In vitro and in silico profiling to assist pharmaceutical development
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Effects of L-glutamate and ADP on immunomodulation of microglia, relevance to stroke
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The treatment of bacterial disease of plants by bacteriophage coated nanoparticles
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Impact of end groups of PLGA on polymer properties and ocular implant performance
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Examining cholinergic fuction in the ventral tegmental area and dorsal hippocampus
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Metabolomic modelling and applications in inflammatory bowel diseases
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Design of vaccine nanotechnology-based delivery systems, the effect of CpGODN TLR9 agonist-protein antigen conjugates anchored to liposomes
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Analysis of CSPα mutants that cause adult-onset neuronal ceroid lipofuscinosis
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Investigating the role of neutrophils in Leishmania mexicana infection
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Application of hyperspectral imaging in pharmaceutical analysis
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Chemical characterization and biological activity of African propolis
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The effects of head restraint on the sleep architecture of mice
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Formation of optimised particles for formulation and processing
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Information provision in ADHD, evaluation of internet resources and the needs of school teachers
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Synthesis and evaluation of targeted dendrisomes as novel gene and drug delivery systems for cancer therapy
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Multi-component crystalline systems based on supramolecular networks
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Miniature wireless deep-brain stimulator and EEG-recording device, implications for the treatment of schizophrenia
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Structural insights into pharmaceutical solids from synchrotron and laboratory x-ray powder diffraction data
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Developing systems for imaging immune responses in vivo
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Mechanistic pharmacokinetic / pharmacodynamic modelling of acute inflammatory challenge models
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Synthesis and evaluation of novel non-viral gene delivery systems for prostate cancer targeting
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Immunological control of toxoplasma gondii infection
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Process intensification through electric field enhanced crystallisation and particle separation
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Control of human inflammatory and cell response by novel and classical steroids
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The potential of polymeric nanoparticles for oral delivery of insulin
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Development of a method for the detection and quantification of the reaction products formed between aldehydes and proteins using high resolution mass spectrometry
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Sonophoretic delivery of a model macromolecular drug
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Analysis of the phytochemical composition and anti-inflammatory properties of Lovage
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Synthesis and biological evaluation of selective inhibitory kappa B kinase-alpha (IKKa) inhibitors for the treatment of prostate and pancreatic cancer
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Design and synthesis of IKK1 inhibitors for the treatment of hormone refractory prostate cancer
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Synthesis of inhibitors of the IKK-complex for the treatment of prostate cancer
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Phytochemical and biological investigation of Lathyrus linofilius as a possible treatment in diabesity
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Novel intranasal GNRs-DNA vaccines against human papillomavirus infection
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Novel applications of advanced optical microscopy for microbiology
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Design and evaluation of ophthalmic formulations in an unlicensed medicines manufacturing unit
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Development of tumour-targeted delivery systems entrapping plumbagin for cancer therapy
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The role of mitochondria in regulating smooth muscle cell proliferation and migration in pulmonary hypertension
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Molecular analysis of MAP kinase kinase signaling in Leishmania
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Function and localization of Leishmania mexicana MAP kinase 2
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Measurement, optimisation and control of particle properties in pharmaceutical manufacturing processes
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Evaluation of amoxicillin, metronidazole and gentamicin dosage regimens for use in antibiotic prophylaxis in colorectal surgery
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Sex-influenced histopathological changes and the immunity during Toxoplasma gondii infection
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A robust machine learning approach for the prediction of allosteric binding sites
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A systems approach to determine how Toxoplasma gondii Infection causes neuropsychiatric disease
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An investigation of the neural circuitry that mediates inhibitory signalling within the lateral habenula
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The impact hypoxia on nanomedicine uptake and efflux in human breast cancer cells
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Discovering the biological and clinical implications of modulating glucocorticoid action using metabolomic profiling of human plasma samples
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Profiling of propolis samples from UK, Indonesia and sub-Saharan Africa and isolation of some pure components
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Self-assembling silk hydrogels for mesenchymal stem cell and drug delivery
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Structural investigations with high pressure techniques and multicomponent systems
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The use of non-ionic surfactant vesicles to prevent radiocontrast media-associated damage
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Investigating novel inhibitors of essential Leishmania mexicana kinases GSK3β and MPK4
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Targeted of cannabinoids in hair and androgens in saliva and untargeted profiling of the effects of exercise
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Characterizing novel protease activated receptor 2 compounds for potential use in examining depression-like behavior
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Nucleation and growth of pharmaceutical crystals
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Design of novel delivery systems to probe alternative routes of administration for a self-amplifying RNA rabies vaccine
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Development of non-ionic surfactant vesicles for inhaled drug delivery
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Microfluidic manufacturing and development of a liposomal vaccine for Clostridium difficile
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Investigating alternative delivery systems for self-Amplifying RNA vaccines
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High pressure as a tool for polymorph screening in small organic molecules
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Control of crystalline particle properties by spray drying
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Combined wet milling crystallisation methods for particle engineering
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Aerodynamic engineering of a pulmonary prime-pull vaccine against Tuberculosis
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New methods for the production of oral dosage forms
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Does the N-terminally truncated sphingosine-1-phosphate receptor 2 promote extracellular regulated Kinase-1/2, c-Jun N-Terminus Kinase and p38 Mitogen-activated protein Kinase activation in breast cancer cells, fibroblasts and embryonic kidney cells?
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Development of a small animal of cardiac contractility and calcium/calmodulin-dependent protein kinase II
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Characterisation of genetic risk factors for mental illness in rodent models, impact of Map2k7+/- and Fxyd6-/- mice on neural systems and working memory
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The role of a monomer/dimer equilibrium and the C-terminal tail in regulating translocation of sphingosine kinase 1 to the plasma membrane of breast cancer cells
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Regulation of p42/p44 mitogen activated protein kinase by sphingosine-1-phosphate in embryonic stem cells
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Application of matrix-assisted laser desorption/ionisation (MALDI) imaging mass spectrometry and high resolution Fourier transform mass spectrometry for profiling pharmaceuticvals and biomarkers in a variety of biological samples
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The role of sphingosine kinases and dihydroceramide desaturase in cell survival/apoptosis and inflammation pathways
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In vitro anti-diabetic and anti-obesity activities of compounds from the Cuban medicinal plant, Allophylus cominia (L.) Sw
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Integrated bioprocessing for the sustainable manufacture of poly (methyl methacrylate) precursors
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Silk fibroin nanoparticles : in vitro performance of a putative anticancer nanomedicine
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Application of population pharmacokinetic-pharmacodynamic modelling evaluate and optimise aminoglycoside therapy in patients with cystic fibrosis
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Effects of OGG1 activation on mitochondrial function in response to oxidative stress
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Determining the impact of neocortex size changes on information processing : implications for neurodevelopmental disorders
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Novel camel milk-derived proteins and their application in the management of acne vulgaris
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Engineering Streptomyces clavuligerus for efficient growth on sustainable carbon sources
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Identification of bioactive secondary metabolites from mangrove plant Avicennia lanata and its endophytic fungi by using metabolomics
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Evaluation of the role of mast cells in parasitic infection
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High pressure polymer science, routes to drug delivery
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The use of infrared spectroscopy to monitor bio-catalytic processes
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Palmitoylation in neurodegeneration, analysis of cysteine-string protein mutants linked with neuronal ceroid lipofuscinosis
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Towards quantifying the intracellular trafficking of silk nanoparticles in cancer cells, establishing biomarkers in the laboratory setting for the characterisation of subcellular fractions
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The effects of JNK isoform knockdown on cell growth and death in HUVECs and MCF-7 cells
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Observation of the impact of reactive oxygen species-inducers on the metabolomes of pulmonary artery smooth muscle cells and retinal pigment epithelial cells
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Examination of the effect of the method of preparation of niosomes with influenza antigen on immune response
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Investigating the neuroprotective properties of PAR2
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Antimicrobial stewardship in the management of sepsis in maternity hospitals - a mixed methodology study
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Combined chemo-radiotherapy utilising Olaparib and Mirin in combination with X-rays and targeted radionuclide therapy
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Development of tumour-targeted gene delivery systems for intravenous cancer therapy
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Studies on the activity of selected plants against biofilms of Pseudomonas aeruginosa strain PA14
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Transcriptional regulation of the human VIPR2 gene
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A comparison of the chemical and potential anti-inflammatory effects of freeze dried and spray dried Aloe vera
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The effects of 7β-OH Epiandrosterone on Cytokine production by human immune cells
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