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Early application of mechanistic PKPD modelling to guide the preclinical development of a therapeutic mAb targeting complement receptor 2 (CR2/CD21) as a novel target for the treatment of autoimmune disease
Creador:
Hooper-Greenhill, Edward
Fecha:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Homogeneous hydrogenation and photochemistry as tools in pharmaceutical process development
Creador:
Shaalan, Youssef
Fecha:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of lysine acylating small molecules for covalent kinase inhibition
Creador:
Fournier, Julie C. L.
Fecha:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel heterocyclic ligands for the lipid kinase PI4KIIIβ : a chemical biology approach
Creador:
Cosgrove, Brett
Fecha:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
A medicinal chemistry approach towards brodomain epigenetic modulators
Creador:
Law, Robert Peter
Fecha:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis and optimisation of novel molecules to probe epigenetic mechanisms with applications in the treatment of inflammatory disorders
Creador:
Diallo, Hawa
Fecha:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development and evaluation of a method for the quantitative determination of a monoclonal antibody using capillary electrophoresis-high resolution mass spectrometry
Creador:
Snell, Richard
Fecha:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The use of structure-based drug design to optimise protein-ligand interactions
Creador:
Bertrand, Sophie
Fecha:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of αvβ6 antagonists as potential idiopathic pulmonary fibrosis agents
Creador:
Anderson, Niall A.
Fecha:
2013
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Electrochemically enabled synthesis of substituted isoxazolines
Creador:
Holman, Samuel David Lee
Fecha:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
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