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GlaxoSmithKline
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Development and understanding of rhodium-catalysed conjugate arylation for process chemistry applications
创造者:
Lovelock, Stephen
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Expanding the scope of asymmetric redox-relay oxidative Heck transformations
创造者:
Bonfield, Holly E.
日期:
2022
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Exploiting DNA-encoded library : technology for the discovery of novel antibody recruiting molecules against LOX-1
创造者:
Macfarlane, Katherine F.
日期:
2022
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis and biological evaluation of novel small molecule bromodomain inhibitors
创造者:
Stafford, Kayleigh
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Catalytic methods for etherification reactions
创造者:
Whitaker, Luke
日期:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigating streptomyces clavuligerus linear replicons for improved clavulanic acid production
创造者:
Mohit, Elmira
日期:
2023 and 2024
Funder:
Biotechnology and Biological Sciences Research Council
,
GlaxoSmithKline
, and
Industrial Biotechnology Innovation Centre
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Synthetic approaches to heterocyclic systems of pharmaceutical relevance
创造者:
Green, Luke
日期:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Early application of mechanistic PKPD modelling to guide the preclinical development of a therapeutic mAb targeting complement receptor 2 (CR2/CD21) as a novel target for the treatment of autoimmune disease
创造者:
Hooper-Greenhill, Edward
日期:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Homogeneous hydrogenation and photochemistry as tools in pharmaceutical process development
创造者:
Shaalan, Youssef
日期:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of lysine acylating small molecules for covalent kinase inhibition
创造者:
Fournier, Julie C. L.
日期:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel heterocyclic ligands for the lipid kinase PI4KIIIβ : a chemical biology approach
创造者:
Cosgrove, Brett
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
A medicinal chemistry approach towards brodomain epigenetic modulators
创造者:
Law, Robert Peter
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis and optimisation of novel molecules to probe epigenetic mechanisms with applications in the treatment of inflammatory disorders
创造者:
Diallo, Hawa
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development and evaluation of a method for the quantitative determination of a monoclonal antibody using capillary electrophoresis-high resolution mass spectrometry
创造者:
Snell, Richard
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The use of structure-based drug design to optimise protein-ligand interactions
创造者:
Bertrand, Sophie
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of αvβ6 antagonists as potential idiopathic pulmonary fibrosis agents
创造者:
Anderson, Niall A.
日期:
2013
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Electrochemically enabled synthesis of substituted isoxazolines
创造者:
Holman, Samuel David Lee
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
αV integrin antagonists for the treatment of idiopathic pulmonary fibrosis
创造者:
Thompson, James
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of electrochemical based sensors in support of toxicokinetic and pharmacokinetics
创造者:
Mahammed, Farjana
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of photoaffinity labelling technologies for small molecule drug discovery - a case study targeting bromodomains
创造者:
Fallon, David
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New methods for the synthesis of pharmaceutical azacycles
创造者:
Clark, Peter
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New hydrogen atom transfer methodologies for synthesis
创造者:
Turner, Oliver
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
创造者:
Heslop, Teresa Louise
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Hi-JAK-ing the ubiquitin system : the design and physicochemical optimisation of JAK PROTACs
创造者:
Shah, Rishi R.
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of bioisosteres to modulate molecular properties in medicinal chemistry
创造者:
Measom, Nicholas
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigations of the synthesis and properties of romodomain and extra-terminal domain proteolysis targeting chimeras
创造者:
Priestner, John C.
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of chemical probes for non-BET bromodomains
创造者:
Clegg, Michael A.
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The use of contemporary chemoproteomic techniques in antimalarial target identification
创造者:
Tucker, Jessie S.
日期:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New route investigation and process development in the synthesis of GSK221149
创造者:
Roberts, Alastair
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of targeted BET inhibitors
创造者:
Robertson, Craig Michael
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel C-C bond formation strategies for access to secondary and tertiary amides enabled by new synthetic technologies
创造者:
Williams, Jason D.
日期:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel approaches targeting phosphoinositide 3-kinase delta
创造者:
Spencer, Jonathan Andrew
日期:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis of non-natural base-pairs : towards site-specific functionalisation of nucleic acids
创造者:
Buchanan, Helena Stubbe
日期:
2021 and 2020
Funder:
GlaxoSmithKline
and
EPSRC Centre for Doctoral Training in Technology Enhanced Chemical Synthesis
Department, School or Faculty:
Department of Pure and Applied Chemistry
Preclinical development of a treatment for systemic lupus erythematosus
创造者:
Murray, Erin
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of small molecule splice-switchers as inducers of apoptosis
创造者:
Campbell, Emma
日期:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Pharmacological characterisation of small molecule RGD-mimetics targeting αvβ6-mediated activation of TGFβ in idiopathic pulmonary fibrosis
创造者:
Slack, Robert J.
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
The design, synthesis and optimisation of calcium release-activated calcium (CRAC) channel inhibitors and mitochondrial permeability transition pore (mPTP) modulators, using phenotypic screening
创造者:
Lacroix, Yannick
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of novel epigenetic modulators
创造者:
Jones, Katherine
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of chemical probes for non-BET bromodomains
创造者:
Theodoulou, Natalie
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
创造者:
Teague, Simon Peter
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Design and synthesis of dimethylisoxazole quinolines as BET inhibitors
创造者:
Wellaway, Christopher Roland
日期:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of chemo- and regioselective reactions of boron systems
创造者:
Clohessy, Thomas A.
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New chemical approaches for the development of targeted protein degradation
创造者:
Lithgow, Hannah
日期:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Targeted protein degradation as a new approach to drug discovery
创造者:
Tinworth, Christopher Patrick
日期:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel biocatalytic strategies for the synthesis of N-functionalised amino acids
创造者:
Hyslop, Julia
日期:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of lysine-targeted irreversible inhibitors of PI3Kδ
创造者:
Dalton, Samuel E.
日期:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
创造者:
Tame, Christopher J.
日期:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel PI3Kδ inhibitors for the treatment of inflammatory diseases
创造者:
Taylor, Jonathan Andrew
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Use of fragment-based drug discovery to identify novel drug molecules for challenging biological targets, including protein-protein interactions
创造者:
White, Gemma Victoria
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies towards the synthesis and labelling of bioactive peptides
创造者:
Stewart, Sam
日期:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
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Barham, Joshua Philip
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Biotechnology and Biological Sciences Research Council
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1
EPSRC Centre for Doctoral Training in Technology Enhanced Chemical Synthesis
1
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77
Strathclyde Institute of Pharmacy and Biomedical Sciences
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