Thesis
Chromosome segregation during Streptomyces coelicolor growth and development
- Creator
- Rights statement
- Awarding institution
- University of Strathclyde
- Date of award
- 2014
- Thesis identifier
- T13959
- Qualification Level
- Qualification Name
- Department, School or Faculty
- Abstract
- In Streptomyces coelicolor DNA segregation is, in part, controlled by the proteins ParA and ParB. Segregation is achieved by ParB binding to parS sites, located near oriC on the bacterial chromosome, and ParA providing the separation energy for segregation. Several mutant strains containing a fluorescently tagged oriC and deletions in parA or parB were created and their growth and positioning of chromosomes, as seen by fluorescent microscopy, were studied over the different stages of its life cycle. Here I show the various differences caused by these mutations within S. coelicolor and highlight potential roles of the Par proteins in dictating the size of spores.
- Resource Type
- DOI
- Date Created
- 2014
- Former identifier
- 1217355
Relations
Contenu
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File | 2021-07-02 | University of Strathclyde |