Thesis

Characterisation of an expandable valve testing apparatus for the development of growth compensating paediatric heart valves

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Awarding institution
  • University of Strathclyde
Date of award
  • 2015
Thesis identifier
  • T14220
Person Identifier (Local)
  • 201471862
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Qualification Name
Department, School or Faculty
Abstract
  • Congenital heart disease is a serious problem affecting up to 9 in every 1,000 babies born in UK. When such a baby is born with a damaged heart valve, it can seriously affect the blood flow through the heart and the entire body. Therefore they have to undergo a life-threatening surgery to have a prosthetic aortic valve replacement. As the paediatric heart is growing, the prosthetic valve should be growing as well, but currently no expandable prosthesis yet exists. During their lifetime, the child has to undergo several serious surgeries which are a burden to them and the options are still limited. An expandable heart valve could compensate these surgeries. Instead of experiencing multiple surgeries, they could have the only one at the beginning of their life. The normal valve opens and closes approximately 103,000 times each day and a prosthetic valve needs to survive at least 200 million cycles to prove that it is durable. The aim of this project is to design and develop an expandable holder that could be deployed in testing of a growth compensating paediatric heart valve. An important part of the project is to perform a set of tests in the heart valve tester using the expandable holder. Obtained results from the heart valve tester have been analysed and discussed as well as future considerations have been proposed.
Resource Type
DOI
Date Created
  • 2015
Former identifier
  • 1247891

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