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Increasing the saturation of BET inhibitors
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Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
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The development of small molecules for treatment of idiopathic pulmonary fibrosis (IPF)
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The design and synthesis of small molecule bromodomain inhibitors
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Structural insights into phenoxide containing alkali metal magnesiates with extensions to the d-block
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Structure-guided discovery of a novel steroid-derived family of autotaxin inhibitors based on endogenous allosteric modulators
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Pharmacological characterisation of the 5-HT receptors present on mouse and human hepatic stellate cells and their role in liver fibrosis
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Understanding & exploiting selectivity in nickel-catalysed cross-coupling
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Understanding cholesterol modified nanoparticles as photothermal agents for cardiovascular disease studies
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Investigating and exploiting best practices in hit identification and hit to lead chemistry
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