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New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
Creator:
Teague, Simon Peter
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Design and synthesis of dimethylisoxazole quinolines as BET inhibitors
Creator:
Wellaway, Christopher Roland
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of chemo- and regioselective reactions of boron systems
Creator:
Clohessy, Thomas A.
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New chemical approaches for the development of targeted protein degradation
Creator:
Lithgow, Hannah
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Targeted protein degradation as a new approach to drug discovery
Creator:
Tinworth, Christopher Patrick
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel biocatalytic strategies for the synthesis of N-functionalised amino acids
Creator:
Hyslop, Julia
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of lysine-targeted irreversible inhibitors of PI3Kδ
Creator:
Dalton, Samuel E.
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
Creator:
Tame, Christopher J.
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel PI3Kδ inhibitors for the treatment of inflammatory diseases
Creator:
Taylor, Jonathan Andrew
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Use of fragment-based drug discovery to identify novel drug molecules for challenging biological targets, including protein-protein interactions
Creator:
White, Gemma Victoria
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
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