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Automated, quantitative process analysis by NMR
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The design, synthesis and optimisation of epigenetic mechanism inhibitors
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The synthesis & optimisation of irreversible ITK inhibitors as a potential new treatment for severe asthma
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The development of small molecule inhibitors for fibrosis drug discovery
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Development of novel inhibitors of carbohydrate-processing targets involved in Mycobacterium tuberculosis cell wall biosynthesis
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Effects of OGG1 activation on mitochondrial function in response to oxidative stress
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Mechanistic pharmacokinetic / pharmacodynamic modelling of acute inflammatory challenge models
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Studies and improvement of molecular docking methods in rigid and flexible receptors
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The design, synthesis and optimisation of kinase inhibitors as potential anti-inflammatory agents
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Development of the C-methyltransferases NovO and CouO for biocatalytic Friedel-Crafts alkylation
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Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
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Synthetic approaches to heterocyclic systems of pharmaceutical relevance
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Catalytic methods for etherification reactions
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Investigating streptomyces clavuligerus linear replicons for improved clavulanic acid production
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The design and synthesis of small molecule bromodomain inhibitors
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Homogeneous hydrogenation and photochemistry as tools in pharmaceutical process development
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The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
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Novel PI3Kδ inhibitors for the treatment of inflammatory diseases
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Chemoselective C-H functionalisation of aliphatic azacycles : utilisation of electrophilic iodine as a mild oxidant
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Novel heterocyclic ligands for the lipid kinase PI4KIIIβ : a chemical biology approach
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