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Synthesis and biological evaluation of novel small molecule bromodomain inhibitors
Creator:
Stafford, Kayleigh
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Exploiting DNA-encoded library : technology for the discovery of novel antibody recruiting molecules against LOX-1
Creator:
Macfarlane, Katherine F.
Date:
2022
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Approaches to lead generation for idiopathic pulmonary fibrosis targets
Creator:
Duffy, Emma
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Mechanistic pharmacokinetic / pharmacodynamic modelling of acute inflammatory challenge models
Creator:
Willis, Robert
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
The development of small molecule inhibitors for fibrosis drug discovery
Creator:
Miller, Lisa Margaret
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The synthesis & optimisation of irreversible ITK inhibitors as a potential new treatment for severe asthma
Creator:
Campos, Sébastien André
Date:
2013
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Automated, quantitative process analysis by NMR
Creator:
Watson, Simon Andrew
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of the C-methyltransferases NovO and CouO for biocatalytic Friedel-Crafts alkylation
Creator:
Sadler, Joanna C.
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of kinase inhibitors as potential anti-inflammatory agents
Creator:
Harrison, Zoë A.
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies and improvement of molecular docking methods in rigid and flexible receptors
Creator:
Le Gall, Armelle
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Effects of OGG1 activation on mitochondrial function in response to oxidative stress
Creator:
Katchur, Steven R.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
Creator:
Heslop, Teresa Louise
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Strathclyde Institute of Pharmacy and Biomedical Sciences
Development of novel inhibitors of carbohydrate-processing targets involved in Mycobacterium tuberculosis cell wall biosynthesis
Creator:
Whitehurst, Ben
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of epigenetic mechanism inhibitors
Creator:
Campbell, Matthew
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New methods for the construction of selectively difluorinated carbocycles
Creator:
McCarter, Adam William
Date:
2018
Funder:
GlaxoSmithKline
and
Carnegie Trust for the Universities of Scotland
Department, School or Faculty:
Department of Pure and Applied Chemistry
Single electron transfer in organic synthesis targeted towards sustainable manufacture
Creator:
Barham, Joshua Philip
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthetic approaches to heterocyclic systems of pharmaceutical relevance
Creator:
Green, Luke
Date:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of phosphoinositide-3-kinase (PI3K) inhibitors as potential anti-inflammatory agents
Creator:
Hardy, Charlotte
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
Creator:
Summers, Declan M.
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Sustainable cross-couplings for pharmaceutical scale-up using aryldiazonium salts
Creator:
Colleville, Aymeric Pierre
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
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