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Development and understanding of rhodium-catalysed conjugate arylation for process chemistry applications
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Synthesis and biological evaluation of novel small molecule bromodomain inhibitors
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Next-generation transcriptional activators for the treatment of Friedreich’s Ataxia
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The design and synthesis of small molecule inhibitors of mTOR Kinase for the treatment of idiopathic pulmonary fibrosis
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Development of ynamines as next-generation bioorthogonal tagging reagents
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Synthesis of non-natural base-pairs : towards site-specific functionalisation of nucleic acids
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Development of small molecule splice-switchers as inducers of apoptosis
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New chemical approaches for the development of targeted protein degradation
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Chemoselective C-H functionalisation of aliphatic azacycles : utilisation of electrophilic iodine as a mild oxidant
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Aromatic ynamines : a new bio-orthogonal reactive group for step-efficient, sequential bioconjugation
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