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New chemical approaches for the development of targeted protein degradation
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Development of lysine-targeted irreversible inhibitors of PI3Kδ
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Pharmacological characterisation of small molecule RGD-mimetics targeting αvβ6-mediated activation of TGFβ in idiopathic pulmonary fibrosis
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The interplay of multiple ADME mechanisms : prediction of hepatic drug-drug interactions from in vitro
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New treatments for inflammatory diseases : optimisation and understanding of key processes
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Novel heterocyclic ligands for the lipid kinase PI4KIIIβ : a chemical biology approach
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Electrochemically enabled synthesis of substituted isoxazolines
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The design, synthesis and optimisation of CCR4 antagonists for the treatment of asthma
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Utilisation of rearrangement chemistry in the synthesis of novel fluorinated ring systems : a computational and experimental study
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The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
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