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Application of bioisosteres to modulate molecular properties in medicinal chemistry
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Investigations of the synthesis and properties of romodomain and extra-terminal domain proteolysis targeting chimeras
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The design and synthesis of chemical probes for non-BET bromodomains
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The use of contemporary chemoproteomic techniques in antimalarial target identification
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New route investigation and process development in the synthesis of GSK221149
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The design and synthesis of targeted BET inhibitors
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Novel C-C bond formation strategies for access to secondary and tertiary amides enabled by new synthetic technologies
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Novel approaches targeting phosphoinositide 3-kinase delta
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Synthesis of non-natural base-pairs : towards site-specific functionalisation of nucleic acids
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Development of small molecule splice-switchers as inducers of apoptosis
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