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Synthesis and biological evaluation of novel small molecule bromodomain inhibitors
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Exploiting DNA-encoded library : technology for the discovery of novel antibody recruiting molecules against LOX-1
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Approaches to lead generation for idiopathic pulmonary fibrosis targets
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Mechanistic pharmacokinetic / pharmacodynamic modelling of acute inflammatory challenge models
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The development of small molecule inhibitors for fibrosis drug discovery
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The synthesis & optimisation of irreversible ITK inhibitors as a potential new treatment for severe asthma
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Automated, quantitative process analysis by NMR
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Development of the C-methyltransferases NovO and CouO for biocatalytic Friedel-Crafts alkylation
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The design, synthesis and optimisation of kinase inhibitors as potential anti-inflammatory agents
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Studies and improvement of molecular docking methods in rigid and flexible receptors
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Effects of OGG1 activation on mitochondrial function in response to oxidative stress
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Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
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Development of novel inhibitors of carbohydrate-processing targets involved in Mycobacterium tuberculosis cell wall biosynthesis
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The design, synthesis and optimisation of epigenetic mechanism inhibitors
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New methods for the construction of selectively difluorinated carbocycles
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Single electron transfer in organic synthesis targeted towards sustainable manufacture
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Synthetic approaches to heterocyclic systems of pharmaceutical relevance
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The design, synthesis and optimisation of phosphoinositide-3-kinase (PI3K) inhibitors as potential anti-inflammatory agents
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Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
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Sustainable cross-couplings for pharmaceutical scale-up using aryldiazonium salts
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