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Investigation of LPA₁ receptor antagonism / ATX inhibition by a scaffold hopping aproach and SAR analysis
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The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
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Evaluating the application and limitations of bio-based solvents within organic synthesis
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The development of small molecule inhibitors for fibrosis drug discovery
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Expedient access to C-aryl linked saturated heterocyclic motifs
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The design and synthesis of molecular tools for probing biological function
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The development of novel organocatalytic and transition-metal catalysed methodologies for amide bond formation
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New methods for the construction of selectively difluorinated carbocycles
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Approaches to lead generation for idiopathic pulmonary fibrosis targets
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Investigations into the generation and pleiotropic reactivity modes of the nitrile imine 1,3-dipole
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