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Synthesis and biological evaluation of novel small molecule bromodomain inhibitors
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Investigation into novel antibacterial agents that will bind at GyrA/ParC or GyrB/ParE subunits of DNA gyrase/topoimerase IV
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The design and synthesis of chemical probes for non-BET bromodomains
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Methods of in-situ monitoring of suspension polymerisation for process understanding and optimisation
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New chemical approaches for the development of targeted protein degradation
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Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
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The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
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Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
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Forensic RNA analysis for estimating the age of body fluid stains
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Searching for mechanistic insights in complex reaction pathways
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