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Investigations of the synthesis and properties of romodomain and extra-terminal domain proteolysis targeting chimeras
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Application of bioisosteres to modulate molecular properties in medicinal chemistry
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Hi-JAK-ing the ubiquitin system : the design and physicochemical optimisation of JAK PROTACs
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Understanding the hepatic disposition of statins to improve predictions of safety and efficacy
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New hydrogen atom transfer methodologies for synthesis
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New methods for the synthesis of pharmaceutical azacycles
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Development of photoaffinity labelling technologies for small molecule drug discovery - a case study targeting bromodomains
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Application of electrochemical based sensors in support of toxicokinetic and pharmacokinetics
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The development and evaluation of a method for the quantitative determination of a monoclonal antibody using capillary electrophoresis-high resolution mass spectrometry
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Synthesis and optimisation of novel molecules to probe epigenetic mechanisms with applications in the treatment of inflammatory disorders
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