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Development of photoaffinity labelling technologies for small molecule drug discovery - a case study targeting bromodomains
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Structure-guided approaches to the design of novel autotaxin inhibitors
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Development of the C-methyltransferases NovO and CouO for biocatalytic Friedel-Crafts alkylation
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Studies and improvement of molecular docking methods in rigid and flexible receptors
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Development towards prospective modelling of in vivo rabbit QTc prolongation
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The design and synthesis of targeted BET inhibitors
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New route investigation and process development in the synthesis of GSK221149
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Approaches to lead generation for idiopathic pulmonary fibrosis targets
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Development of small molecule splice-switchers as inducers of apoptosis
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New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
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