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The design and synthesis of novel epigenetic modulators
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Design and synthesis of dimethylisoxazole quinolines as BET inhibitors
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The development of chemo- and regioselective reactions of boron systems
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New chemical approaches for the development of targeted protein degradation
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Targeted protein degradation as a new approach to drug discovery
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The design and synthesis of probe molecules to validate the inhibition of epigenetic mechanisms for phenotypic responses
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The synthesis and optimisation of toll-like receptor agonists as potential immunomodulatory agents
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The design, synthesis and optimisation of phosphoinositide-3-kinase (PI3K) inhibitors as potential anti-inflammatory agents
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The design, synthesis and optimisation of calcium release-activated calcium (CRAC) channel inhibitors and mitochondrial permeability transition pore (mPTP) modulators, using phenotypic screening
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Hi-JAK-ing the ubiquitin system : the design and physicochemical optimisation of JAK PROTACs
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