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GlaxoSmithKline
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Development of novel inhibitors of carbohydrate-processing targets involved in Mycobacterium tuberculosis cell wall biosynthesis
Creator:
Whitehurst, Ben.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
New treatments for inflammatory diseases, optimisation and understanding of key processes
Creator:
Davies, Suzanne H.
Date:
2012
Funder:
GlaxoSmithKline
Department, School or Faculty:
WestCHEM. and Department of Pure and Applied Chemistry.
The synthesis & optimisation of irreversible ITK inhibitors as a potential new treatment for severe asthma
Creator:
Campos, Sébastien André.
Date:
2013
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Utilisation of rearrangement chemistry in the synthesis of novel fluorinated ring systems, a computational and experimental study
Creator:
Orr, David George Alexander.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The design, synthesis and optimisation of epigenetic mechanism inhibitors
Creator:
Campbell, Matthew.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Automated, quantitative process analysis by NMR
Creator:
Watson, Simon Andrew.
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
New methods for the construction of selectively difluorinated carbocycles
Creator:
McCarter, Adam William.
Date:
2018
Funder:
Carnegie Trust for the Universities of Scotland
and
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The design, synthesis and optimisaion of CCR4 antagonists for the treatment of asthma
Creator:
Miah, Afjal Hussain.
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Single electron transfer in organic synthesis targeted towards sustainable manufacture
Creator:
Barham, Joshua Philip.
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The interplay of multiple ADME mechanisms, prediction of hepatic drug-drug interactions from in vitro
Creator:
Hobbs, Michael.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The design, synthesis and optimisation of phosphoinositide-3-kinase (PI3K) inhibitors as potential anti-inflammatory agents
Creator:
Hardy, Charlotte.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Sustainable cross-couplings for pharmaceutical scale-up using aryldiazonium salts
Creator:
Colleville, Aymeric Pierre.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The synthesis and optimisation of toll-like receptor agonists as potential immunomodulatory agents
Creator:
Tape, Daniel Terence.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Investigating and exploiting best practices in hit identification and hit to lead chemistry
Creator:
Borthwick, Jennifer.
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
Pharmacological characterisation of the 5-HT receptors present on mouse and human hepatic stellate cells and their role in liver fibrosis
Creator:
Barrett, Victoria J.
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry.
The development of small molecules for treatment of idiopathic pulmonary fibrosis (IPF)
Creator:
Campbell-Crawford, Matthew H. J.
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
Creator:
Wood, Susanna Helen
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Increasing the saturation of BET inhibitors
Creator:
Dixon, Joseph Edward
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Chemoselective C–H functionalisation of aliphatic azacycles : utilisation of electrophilic iodine as a mild oxidant
Creator:
Griffiths, Robert Joseph
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of probe molecules to validate the inhibition of epigenetic mechanisms for phenotypic responses
Creator:
Hayhow, Thomas G.
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
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