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A medicinal chemistry approach towards brodomain epigenetic modulators
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Synthesis and optimisation of novel molecules to probe epigenetic mechanisms with applications in the treatment of inflammatory disorders
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Novel C-C bond formation strategies for access to secondary and tertiary amides enabled by new synthetic technologies
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Studies towards the synthesis and labelling of bioactive peptides
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Novel approaches targeting phosphoinositide 3-kinase delta
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Iron-catalysed cross-couplings of secondary alkyl Grignard reagents
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Increasing the saturation of BET inhibitors
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Mechanistic pharmacokinetic / pharmacodynamic modelling of acute inflammatory challenge models
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Investigating and exploiting best practices in hit identification and hit to lead chemistry
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Chan-Lam animation studies : solving the chemotype reactivity issue
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