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Pharmacological characterisation of small molecule RGD-mimetics targeting αvβ6-mediated activation of TGFβ in idiopathic pulmonary fibrosis
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The use of structure-based drug design to optimise protein-ligand interactions
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The design, synthesis and optimisation of CCR4 antagonists for the treatment of asthma
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αV integrin antagonists for the treatment of idiopathic pulmonary fibrosis
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The design, synthesis and optimisation of αvβ6 antagonists as potential idiopathic pulmonary fibrosis agents
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Development of lysine-targeted irreversible inhibitors of PI3Kδ
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Electrochemically enabled synthesis of substituted isoxazolines
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Novel heterocyclic ligands for the lipid kinase PI4KIIIβ : a chemical biology approach
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Chemoselective C-H functionalisation of aliphatic azacycles : utilisation of electrophilic iodine as a mild oxidant
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Novel PI3Kδ inhibitors for the treatment of inflammatory diseases
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