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The design and synthesis of targeted BET inhibitors
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New route investigation and process development in the synthesis of GSK221149
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Approaches to lead generation for idiopathic pulmonary fibrosis targets
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Development of small molecule splice-switchers as inducers of apoptosis
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New dose estimation methods and their application in early drug discovery using intravenous, oral and inhaled routes of administration for new chemical entities
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Effects of OGG1 activation on mitochondrial function in response to oxidative stress
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Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
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Pharmacological characterisation of the 5-HT receptors present on mouse and human hepatic stellate cells and their role in liver fibrosis
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Automated, quantitative process analysis by NMR
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The synthesis & optimisation of irreversible ITK inhibitors as a potential new treatment for severe asthma
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