Thesis

A model for continuous quality improvement of medication use : concepts, methods and applications

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Creator
Awarding institution
  • University of Strathclyde
Date of award
  • 2011
Thesis identifier
  • T13192
Qualification Level
Qualification Name
Department, School or Faculty
Abstract
  • Background Despite the instigation of regulations to ensure that medicinal products entering the market are nontoxic and yield a favourable risk-benefit balance, drug products frequently fail to produce the benefits found in clinical trials and frequently cause harm. The aim of this thesis is to design and operationalise a conceptual framework for monitoring and improving the performance of medication use systems. Objectives (1) To contribute to the conceptual understanding of preventable drug-related morbidity (PDRM) and its causes, (2) to identify components of a model for continuous quality improvement of medication use systems, (3) to develop an instrument to measure the quality of medication use for multiple conditions and (4) to test the instrument for its utility within the proposed quality improvement model. Methods (1) Concepts used in the pharmaco-epidemiological and pharmaceutical care literature were critically reviewed. (2) A structured literature review was conducted in order to summarise the impact of previously tested quality improvement interventions on medication use processes and patient outcomes. (3) A generic framework for explicit quality assessment of medication use was developed and applied to design a medication assessment tool for multiple cardiovascular conditions (MATCVC). (4) Field testing of the MATCVC instrument was undertaken by applications in retrospective surveys conducted in German inpatient (A), Scottish outpatient (B) and Dutch primary care settings (C).
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Note
  • Strathclyde theses - ask staff. Thesis no. : T13192
DOI
Date Created
  • 2011
Former identifier
  • 947621

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