Thesis

Dynamic mechanical analysis of articular cartilage using nanoindentation

Creator
Rights statement
Awarding institution
  • University of Strathclyde
Date of award
  • 2015
Thesis identifier
  • T14209
Person Identifier (Local)
  • 201460246
Qualification Level
Qualification Name
Department, School or Faculty
Abstract
  • The aim of this study was to use nanoindention in a novel attempt to characterize the behaviour of articular cartilage. Using bovine femoral heads, viscoelastic properties of the tissue were determined for five frequency loading magnitudes; 1 Hz, 2 Hz, 5 Hz, 10 Hz, and 25 Hz. Dynamic mechanical analysis was used to measure the δ, storage and loss modulus of the samples. The testing showed that the storage modulus displays frequency dependence up until higher frequencies where the response plateaus and becomes insensitive to frequency. The loss modulus was found to have no frequency dependent qualities. Throughout all frequencies the storage modulus has far greater values than loss modulus, with the disparity between the two increasing with frequency. The excess energy being stored as opposed to lost can cause tissue damage, which potentially is a mechanism of the onset of Osteoarthritis.
Advisor / supervisor
  • Riches, Philip
Resource Type
DOI
Embargo Note
  • The electronic version of this thesis is currently under moratorium due to copyright restrictions. If you are the author of this thesis, please contact the Library to resolve this issue.

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