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Department of Pure and Applied Chemistry
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Structural insights into phenoxide containing alkali metal magnesiates with extensions to the d-block
Creator:
Yeardley, Callum
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Establishing the extent of sample damage and safe limits of laser exposure during live cell analysis with raman spectroscopy
Creator:
Thomson, Caitlin
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Electrochemical and electrogenerated chemiluminescent investigation of ATSs
Creator:
Dokuzparmak, Emre.
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Analytical and Forensic Chemistry CH213 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of small molecule splice-switchers as inducers of apoptosis
Creator:
Campbell, Emma
Date:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
SERS & efficacy assessment of anti-cancer drug-nanoparticle conjugates
Creator:
Cameron, Rachael Yvonne
Date:
2019
Department, School or Faculty:
Department of Pure and Applied Chemistry
Use of raman spectroscopy for the study of brain tumours
Creator:
Hill, Iona Elizabeth
Date:
2021
Funder:
Medical Research Council
,
OPTIMA CDT
, and
Engineering and Physical Sciences Research Council
Department, School or Faculty:
Department of Pure and Applied Chemistry
Portable electrochemical screening of drugs
Creator:
Blake, Rowan
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
New route investigation and process development in the synthesis of GSK221149
Creator:
Roberts, Alastair
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of targeted BET inhibitors
Creator:
Robertson, Craig Michael
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Molecularly imprinted polymers for small cell lung cancer diagnosis
Creator:
Bicak, Tugrul Cem
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigations into the selectivity of iridium catalysts in the hydrogen isotope exchange of aromatic aldehydes and in hydroxyl-directed stereoselective hydrogenation
Creator:
Kidd, Giorgia
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Optimisation of myoglobin as a biocatalyst for reversible deactivation radical polymerisation
Creator:
Chadwick, Robert James
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
A quantitative scale for directing group power in ruthenium(II)-catalysed ortho-directed C-H arylation reactions
Creator:
McIntyre, Jamie
Date:
2017
Department, School or Faculty:
Department of Pure and Applied Chemistry
Quantitative drug imaging of minor groove binders using Raman microscopy
Creator:
Tentellino, Christian
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Advancing main-group-metal mediation in synthesis and catalysis
Creator:
Whitelaw, Michael Thomas
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Topics in Chemistry CH590 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Study of solution processable emissive materials for organic light emitting diodes
Creator:
Breig, Benjamin
Date:
2018
Funder:
Korea Institute for Advancement of Technology
Department, School or Faculty:
Department of Pure and Applied Chemistry and WestCHEM
Structure-guided approaches to the design of novel autotaxin inhibitors
Creator:
Potjewyd, Frances
Date:
2016
Funder:
Engineering and Physical Sciences Research Council
and
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of computer vision in industrially important reactions
Creator:
Yan, Chunhui
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of photoaffinity labelling technologies for small molecule drug discovery - a case study targeting bromodomains
Creator:
Fallon, David
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of electrochemical based sensors in support of toxicokinetic and pharmacokinetics
Creator:
Mahammed, Farjana
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
Creator:
Baker, Blake Jamie Mark
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of bioisosteres to modulate molecular properties in medicinal chemistry
Creator:
Measom, Nicholas
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of chemical probes for non-BET bromodomains
Creator:
Clegg, Michael A.
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of chemical probes for non-BET bromodomains
Creator:
Theodoulou, Natalie
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Use of fragment-based drug discovery to identify novel drug molecules for challenging biological targets, including protein-protein interactions
Creator:
White, Gemma Victoria
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
Creator:
Summers, Declan M.
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of small molecules for treatment of idiopathic pulmonary fibrosis (IPF)
Creator:
Campbell-Crawford, Matthew H. J.
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New hydrogen atom transfer methodologies for synthesis
Creator:
Turner, Oliver
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of small molecule inhibitors of mTOR Kinase for the treatment of idiopathic pulmonary fibrosis
Creator:
Davies, Hannah Rose Marie
Date:
2020
Funder:
GlaxoSmithKline foundation
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigations of the synthesis and properties of romodomain and extra-terminal domain proteolysis targeting chimeras
Creator:
Priestner, John C.
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The use of contemporary chemoproteomic techniques in antimalarial target identification
Creator:
Tucker, Jessie S.
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Preclinical development of a treatment for systemic lupus erythematosus
Creator:
Murray, Erin
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of novel epigenetic modulators
Creator:
Jones, Katherine
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Design and synthesis of dimethylisoxazole quinolines as BET inhibitors
Creator:
Wellaway, Christopher Roland
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of chemo- and regioselective reactions of boron systems
Creator:
Clohessy, Thomas A.
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New chemical approaches for the development of targeted protein degradation
Creator:
Lithgow, Hannah
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Targeted protein degradation as a new approach to drug discovery
Creator:
Tinworth, Christopher Patrick
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of probe molecules to validate the inhibition of epigenetic mechanisms for phenotypic responses
Creator:
Hayhow, Thomas G.
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of calcium release-activated calcium (CRAC) channel inhibitors and mitochondrial permeability transition pore (mPTP) modulators, using phenotypic screening
Creator:
Lacroix, Yannick
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Hi-JAK-ing the ubiquitin system : the design and physicochemical optimisation of JAK PROTACs
Creator:
Shah, Rishi R.
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Design and engineering of myoglobin-based biocatalysts for controlled radical polymerisations
Creator:
Guo, Chao
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Physicochemical studies on spectroscopic characterization, preconcentration, separation, determination and/or chemical speciation of various inorganic and organic complex species in different media
Creator:
El-Shahawi, Mohammad S.
Date:
2013
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigating novel reagents in organic synthesis
Creator:
Dimitrova, Daniela
Date:
2022
Funder:
Engineering and Physical Sciences Research Council
and
GlaxoSmithKline foundation
Department, School or Faculty:
Department of Pure and Applied Chemistry
The search for radicals in unexpected places
Creator:
Clark, Kenneth Forbes
Date:
2022
Funder:
AstraZeneca
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel methods to access tracelessly labelled molecules via iridium-catalysed hydrogen isotope exchange
Creator:
Townsley, J. Conor
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Human bioaccessibility of potentially toxic elements in soils using three in-vitro extraction methods
Creator:
Al-Wahaibi, Bushra Salim
Date:
2012
Funder:
Sultan Qaboos University
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development and study of donor-acceptor Stenhouse adduct junction-functionalised block copolymers
Creator:
Wesseler, Justus Paul
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
New methods for the synthesis of pharmaceutical azacycles
Creator:
Clark, Peter
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development and evaluation of a method for the quantitative determination of a monoclonal antibody using capillary electrophoresis-high resolution mass spectrometry
Creator:
Snell, Richard
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Adhesive formulations for lens applications
Creator:
McCreath, Simson
Date:
2015
Funder:
Polaroid Eyewear
Department, School or Faculty:
Department of Pure and Applied Chemistry
Multipurpose polymer wafers for skin regeneration
Creator:
Man, Ernest
Date:
2023
Department, School or Faculty:
Department of Pure and Applied Chemistry
A medicinal chemistry approach towards brodomain epigenetic modulators
Creator:
Law, Robert Peter
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis enabled drug discovery
Creator:
Hassell-Hart, Storm James
Date:
2017
Funder:
GlaxoSmithKline foundation
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis and optimisation of novel molecules to probe epigenetic mechanisms with applications in the treatment of inflammatory disorders
Creator:
Diallo, Hawa
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel C-C bond formation strategies for access to secondary and tertiary amides enabled by new synthetic technologies
Creator:
Williams, Jason D.
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Elucidation of complex reaction mechanisms through the application of density functional theory
Creator:
Kolodziejczak, Krystian
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Rapid pre-symptomatic diagnosis of sepsis by vibrational spectroscopy
Creator:
Lovergne, Lila
Date:
2018
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies on organic electron donors and their applications in chemistry
Creator:
Cumine, Florimond
Date:
2017
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies towards the synthesis and labelling of bioactive peptides
Creator:
Stewart, Sam
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of peptoid material for cell growth and differentiation
Creator:
El Yaagoubi, Marwa
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel approaches targeting phosphoinositide 3-kinase delta
Creator:
Spencer, Jonathan Andrew
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of novel synthetic and analytic protocols for cationic magnesium complexes relevant to battery applications
Creator:
Brown, Scott
Date:
2023
Department, School or Faculty:
Department of Pure and Applied Chemistry
Advances in the synthesis and application of iridium (I) complexes for use in hydrogen isotope exchange
Creator:
Cochrane, Alison R.
Date:
2012
Department, School or Faculty:
Department of Pure and Applied Chemistry
Iron-catalysed cross-couplings of secondary alkyl Grignard reagents
Creator:
Sanderson, James
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Three-dimensional spectroscopic chemical imaging of pharmaceutical tablets
Creator:
Carruthers, Hannah
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Increasing the saturation of BET inhibitors
Creator:
Dixon, Joseph Edward
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies on the photodegradation of polyurethane foam
Creator:
McKendry, Christina
Date:
2023
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigation into novel antibacterial agents that will bind at GyrA/ParC or GyrB/ParE subunits of DNA gyrase/topoimerase IV
Creator:
McGarry, David
Date:
2019
Funder:
RedX
Department, School or Faculty:
Department of Pure and Applied Chemistry
New iridium-catalysed methods for the hydrogen isotope exchange of pharmaceutically-relevant compounds
Creator:
Knight, Nathan
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Chan-Lam animation studies : solving the chemotype reactivity issue
Creator:
Vantourout, Julien
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Extending peptide search space and self-assembly methods
Creator:
van Teijlingen, Alexander
Date:
2023
Funder:
Engineering and Physical Sciences Research Council
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of lysine acylating small molecules for covalent kinase inhibition
Creator:
Fournier, Julie C. L.
Date:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigating the host defence peptide, LL-37, as an antimicrobial : a Raman microscopic approach
Creator:
Walker, Sam
Date:
2023 and 2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Forensic Chemistry FS938 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Understanding spectral signatures of cancerous disease states
Creator:
Smith, Benjamin R.
Date:
2023
Funder:
Dxcover
Department, School or Faculty:
Department of Pure and Applied Chemistry
Structure activity studies of aminoindole anti-malarial agents to enhance physicochemical properties and safety profile
Creator:
Sandoval Izquierdo, Elena
Date:
2018
Department, School or Faculty:
Department of Pure and Applied Chemistry
New insights into homo- and heterometallic alkali metal amide chemistry
Creator:
Robertson, Gemma Margaret
Date:
2012
Department, School or Faculty:
Department of Pure and Applied Chemistry
A study of the thermal degradation of flexible tdi-based polyurethane foams
Creator:
Todd, Deborah
Date:
2012
Department, School or Faculty:
Department of Pure and Applied Chemistry
Thermal, oxidative and hydrolytic degradation studies of poly(ethylene naphthalate)
Creator:
Turnbull, Louise
Date:
2013
Department, School or Faculty:
Department of Pure and Applied Chemistry
The synthesis and application of tetrahydrobiopterin mimetics
Creator:
McInnes, Craig Robert
Date:
2012
Department, School or Faculty:
Department of Pure and Applied Chemistry
Advances in synthetic, structural and reaction chemistry of zinc and zincate complexes containing alkyl and/or amido ligands
Creator:
Garden, Jennifer Anne
Date:
2014
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of small molecule inhibitors for fibrosis drug discovery
Creator:
Miller, Lisa Margaret
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of natural products as phytotoxic leads for herbicide discovery
Creator:
Littleson, Mairi M.
Date:
2017
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development and investigation of novel chemoselective processes in Pd and Cu catalysis
Creator:
Seath, Ciaran Paul
Date:
2017
Funder:
Carnegie Trust for the Universities of Scotland
Department, School or Faculty:
Department of Pure and Applied Chemistry
Physics-based and deep learning approaches for the determination of solution thermodynamic parameters
Creator:
Fowles, Daniel J.
Date:
2023
Department, School or Faculty:
Department of Pure and Applied Chemistry
Force field development and molecular dynamics simulations of triacylglycerides
Creator:
Cordina, Robert
Date:
2023
Funder:
Mondelēz R&D
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies toward the development of novel coupling reactions
Creator:
Stewart, Alexander J.
Date:
2023
Funder:
Co-funded by GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Methods of in-situ monitoring of suspension polymerisation for process understanding and optimisation
Creator:
Robertson, Barry Thomas
Date:
2020 and 2019
Funder:
Seventh framework programme of the European Community for research and technological development including demonstration activities(FP7)
Department, School or Faculty:
Department of Pure and Applied Chemistry
SERS in the second biological window: towards in-vivo applications
Creator:
Callander, Andrew
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Understanding reactions between Nickel(0) and substrates relevant to cross-coupling reactions
Creator:
Greaves, Megan Elizabeth
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis of non-natural base-pairs : towards site-specific functionalisation of nucleic acids
Creator:
Buchanan, Helena Stubbe
Date:
2021 and 2020
Funder:
GlaxoSmithKline
and
EPSRC Centre for Doctoral Training in Technology Enhanced Chemical Synthesis
Department, School or Faculty:
Department of Pure and Applied Chemistry
Structure-guided discovery of a novel steroid-derived family of autotaxin inhibitors based on endogenous allosteric modulators
Creator:
Clark, Jennifer M.
Date:
2020 and 2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
The solid-state structure of tricyclic antidepressants
Creator:
Lobato, Kiara
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Bioinspired amphipilic polymer conetworks
Creator:
Velasquez, Sara Tatiana Roldan
Date:
2023
Department, School or Faculty:
Department of Pure and Applied Chemistry
Process analytical technologies for particle characterisation and solid form analysis in continuous secondary pharmaceutical manufacturing
Creator:
Lothian, Joanna
Date:
2023
Department, School or Faculty:
Department of Pure and Applied Chemistry
Computational modelling of enzyme activity to speed up biocatalyst redesign
Creator:
Dréanic, Marie-Pierre
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis and characterisation of homometallic (Mg) and heterobimetallic (Na/Mg, K/Mg, K/Zn, Li/Al, Na/Al, K/Al) compounds with alkoxo, alkyl, amido or halo ligands
Creator:
Weatherstone, Susan
Date:
2006
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel synthesis of carbon-carbon mainchain optically active polymers
Creator:
Jana, Satyasankar
Date:
2005
Department, School or Faculty:
Department of Pure and Applied Chemistry
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