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Department of Pure and Applied Chemistry
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Rapid pre-symptomatic diagnosis of sepsis by vibrational spectroscopy
Creator:
Lovergne, Lila
Date:
2018
Department, School or Faculty:
Department of Pure and Applied Chemistry
Advances in synthetic, structural and reaction chemistry of zinc and zincate complexes containing alkyl and/or amido ligands
Creator:
Garden, Jennifer Anne
Date:
2014
Department, School or Faculty:
Department of Pure and Applied Chemistry
Study of solution processable emissive materials for organic light emitting diodes
Creator:
Breig, Benjamin
Date:
2018
Funder:
Korea Institute for Advancement of Technology
Department, School or Faculty:
Department of Pure and Applied Chemistry and WestCHEM
The development of small molecule inhibitors for fibrosis drug discovery
Creator:
Miller, Lisa Margaret
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Thermal, oxidative and hydrolytic degradation studies of poly(ethylene naphthalate)
Creator:
Turnbull, Louise
Date:
2013
Department, School or Faculty:
Department of Pure and Applied Chemistry
A study of the thermal degradation of flexible tdi-based polyurethane foams
Creator:
Todd, Deborah
Date:
2012
Department, School or Faculty:
Department of Pure and Applied Chemistry
SERS & efficacy assessment of anti-cancer drug-nanoparticle conjugates
Creator:
Cameron, Rachael Yvonne
Date:
2019
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies on organic electron donors and their applications in chemistry
Creator:
Cumine, Florimond
Date:
2017
Department, School or Faculty:
Department of Pure and Applied Chemistry
New insights into homo- and heterometallic alkali metal amide chemistry
Creator:
Robertson, Gemma Margaret
Date:
2012
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development and investigation of novel chemoselective processes in Pd and Cu catalysis
Creator:
Seath, Ciaran Paul
Date:
2017
Funder:
Carnegie Trust for the Universities of Scotland
Department, School or Faculty:
Department of Pure and Applied Chemistry
The synthesis and application of tetrahydrobiopterin mimetics
Creator:
McInnes, Craig Robert
Date:
2012
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of natural products as phytotoxic leads for herbicide discovery
Creator:
Littleson, Mairi M.
Date:
2017
Department, School or Faculty:
Department of Pure and Applied Chemistry
A quantitative scale for directing group power in ruthenium(II)-catalysed ortho-directed C-H arylation reactions
Creator:
McIntyre, Jamie
Date:
2017
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigation of LPA₁ receptor antagonism / ATX inhibition by a scaffold hopping aproach and SAR analysis
Creator:
Castagna, Diana
Date:
2016
Department, School or Faculty:
Department of Pure and Applied Chemistry
Structure-guided approaches to the design of novel autotaxin inhibitors
Creator:
Potjewyd, Frances
Date:
2016
Funder:
Engineering and Physical Sciences Research Council
and
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Inorganic Chemistry, Structure and Spectroscopy: Transition Metals and Organometallic Chemistry CH326 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Physical Chemistry 2 CH309 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Structure-guided discovery of a novel steroid-derived family of autotaxin inhibitors based on endogenous allosteric modulators
Creator:
Clark, Jennifer M.
Date:
2020 and 2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Structural insights into phenoxide containing alkali metal magnesiates with extensions to the d-block
Creator:
Yeardley, Callum
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of small molecule bromodomain inhibitors
Creator:
Lucas, Simon Christopher Cranko Alcock
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of small molecules for treatment of idiopathic pulmonary fibrosis (IPF)
Creator:
Campbell-Crawford, Matthew H. J.
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Understanding reaction mechanisms and structure/reactivity relationships in the electrophilic fluorination of enol esters
Creator:
Wood, Susanna Helen
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Increasing the saturation of BET inhibitors
Creator:
Dixon, Joseph Edward
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Computational modelling of enzyme activity to speed up biocatalyst redesign
Creator:
Dréanic, Marie-Pierre
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Iron-catalysed cross-couplings of secondary alkyl Grignard reagents
Creator:
Sanderson, James
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The application of flow chemistry to the synthesis of pharmaceutically privileged heterocycles
Creator:
Baker, Blake Jamie Mark
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigation and application of 3-Oxabicyclo[4.1.0]heptane as a mechanistic target of rapamycin (mTOR) kinase hinge binding fragment
Creator:
Summers, Declan M.
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Chemoselective C-H functionalisation of aliphatic azacycles : utilisation of electrophilic iodine as a mild oxidant
Creator:
Griffiths, Robert Joseph
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Chan-Lam animation studies : solving the chemotype reactivity issue
Creator:
Vantourout, Julien
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Establishing the extent of sample damage and safe limits of laser exposure during live cell analysis with raman spectroscopy
Creator:
Thomson, Caitlin
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of probe molecules to validate the inhibition of epigenetic mechanisms for phenotypic responses
Creator:
Hayhow, Thomas G.
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Studies towards the synthesis and labelling of bioactive peptides
Creator:
Stewart, Sam
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Use of fragment-based drug discovery to identify novel drug molecules for challenging biological targets, including protein-protein interactions
Creator:
White, Gemma Victoria
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel PI3Kδ inhibitors for the treatment of inflammatory diseases
Creator:
Taylor, Jonathan Andrew
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of αvβ6 antagonists and PI3K inhibitors as small molecule therapies for respiratory diseases
Creator:
Tame, Christopher J.
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of lysine-targeted irreversible inhibitors of PI3Kδ
Creator:
Dalton, Samuel E.
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Targeted protein degradation as a new approach to drug discovery
Creator:
Tinworth, Christopher Patrick
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New chemical approaches for the development of targeted protein degradation
Creator:
Lithgow, Hannah
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development of chemo- and regioselective reactions of boron systems
Creator:
Clohessy, Thomas A.
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Design and synthesis of dimethylisoxazole quinolines as BET inhibitors
Creator:
Wellaway, Christopher Roland
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Forensic Chemistry FS938 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of chemical probes for non-BET bromodomains
Creator:
Theodoulou, Natalie
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Electrochemical and electrogenerated chemiluminescent investigation of ATSs
Creator:
Dokuzparmak, Emre.
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Understanding reactions between Nickel(0) and substrates relevant to cross-coupling reactions
Creator:
Greaves, Megan Elizabeth
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Topics in Chemistry CH590 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Analytical and Forensic Chemistry CH213 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Chemistry Specialisation CH477 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Core Chemistry CH479 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Chemistry Specialisation CH480 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Chemistry Specialisation CH482 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Core Chemistry Topics in Drug Discovery CH589 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
Core Topics in Chemistry CH591 exam papers
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of novel epigenetic modulators
Creator:
Jones, Katherine
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of calcium release-activated calcium (CRAC) channel inhibitors and mitochondrial permeability transition pore (mPTP) modulators, using phenotypic screening
Creator:
Lacroix, Yannick
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of small molecule splice-switchers as inducers of apoptosis
Creator:
Campbell, Emma
Date:
2021
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Use of raman spectroscopy for the study of brain tumours
Creator:
Hill, Iona Elizabeth
Date:
2021
Funder:
Medical Research Council
,
OPTIMA CDT
, and
Engineering and Physical Sciences Research Council
Department, School or Faculty:
Department of Pure and Applied Chemistry
Preclinical development of a treatment for systemic lupus erythematosus
Creator:
Murray, Erin
Date:
2014
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis of non-natural base-pairs : towards site-specific functionalisation of nucleic acids
Creator:
Buchanan, Helena Stubbe
Date:
2021 and 2020
Funder:
GlaxoSmithKline
and
EPSRC Centre for Doctoral Training in Technology Enhanced Chemical Synthesis
Department, School or Faculty:
Department of Pure and Applied Chemistry
Portable electrochemical screening of drugs
Creator:
Blake, Rowan
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Methods of in-situ monitoring of suspension polymerisation for process understanding and optimisation
Creator:
Robertson, Barry Thomas
Date:
2020 and 2019
Funder:
Seventh framework programme of the European Community for research and technological development including demonstration activities(FP7)
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis and evaluation of novel small molecule inhibitors of the androgen receptor amino-terminal domain for the treatment of castration-resistant prostate cancer
Creator:
Riley, Christopher
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Metal-free oxidation of unactivated sp3 C–H bonds.
Creator:
Maciuk, Sergej
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Small molecule pH sensors for biological raman imaging
Creator:
Wilson, Liam
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel approaches targeting phosphoinositide 3-kinase delta
Creator:
Spencer, Jonathan Andrew
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel C-C bond formation strategies for access to secondary and tertiary amides enabled by new synthetic technologies
Creator:
Williams, Jason D.
Date:
2018
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of targeted BET inhibitors
Creator:
Robertson, Craig Michael
Date:
2016
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New route investigation and process development in the synthesis of GSK221149
Creator:
Roberts, Alastair
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Molecularly imprinted polymers for small cell lung cancer diagnosis
Creator:
Bicak, Tugrul Cem
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Design and engineering of myoglobin-based biocatalysts for controlled radical polymerisations
Creator:
Guo, Chao
Date:
2021
Department, School or Faculty:
Department of Pure and Applied Chemistry
Optimisation of myoglobin as a biocatalyst for reversible deactivation radical polymerisation
Creator:
Chadwick, Robert James
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigations into the selectivity of iridium catalysts in the hydrogen isotope exchange of aromatic aldehydes and in hydroxyl-directed stereoselective hydrogenation
Creator:
Kidd, Giorgia
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of new chemical tools as crop protecting agents
Creator:
Hamer, Meghan M.
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Advancing main-group-metal mediation in synthesis and catalysis
Creator:
Whitelaw, Michael Thomas
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of peptoid material for cell growth and differentiation
Creator:
El Yaagoubi, Marwa
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Quantitative drug imaging of minor groove binders using Raman microscopy
Creator:
Tentellino, Christian
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of ynamines as next-generation bioorthogonal tagging reagents
Creator:
Peschke, Frederik
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Earlier detection of multiple cancers using ATR-FTIR spectroscopic analysis of human blood serum
Creator:
Sala, Alexandra
Date:
2022
Funder:
Dxcover Ltd.
Department, School or Faculty:
Department of Pure and Applied Chemistry
Three-dimensional spectroscopic chemical imaging of pharmaceutical tablets
Creator:
Carruthers, Hannah
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of computer vision in industrially important reactions
Creator:
Yan, Chunhui
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
The use of contemporary chemoproteomic techniques in antimalarial target identification
Creator:
Tucker, Jessie S.
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of chemical probes for non-BET bromodomains
Creator:
Clegg, Michael A.
Date:
2019
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigations of the synthesis and properties of romodomain and extra-terminal domain proteolysis targeting chimeras
Creator:
Priestner, John C.
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of bioisosteres to modulate molecular properties in medicinal chemistry
Creator:
Measom, Nicholas
Date:
2017
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design and synthesis of small molecule inhibitors of mTOR Kinase for the treatment of idiopathic pulmonary fibrosis
Creator:
Davies, Hannah Rose Marie
Date:
2020
Funder:
GlaxoSmithKline foundation
Department, School or Faculty:
Department of Pure and Applied Chemistry
Hi-JAK-ing the ubiquitin system : the design and physicochemical optimisation of JAK PROTACs
Creator:
Shah, Rishi R.
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New hydrogen atom transfer methodologies for synthesis
Creator:
Turner, Oliver
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
New methods for the synthesis of pharmaceutical azacycles
Creator:
Clark, Peter
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Development of photoaffinity labelling technologies for small molecule drug discovery - a case study targeting bromodomains
Creator:
Fallon, David
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Application of electrochemical based sensors in support of toxicokinetic and pharmacokinetics
Creator:
Mahammed, Farjana
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
αV integrin antagonists for the treatment of idiopathic pulmonary fibrosis
Creator:
Thompson, James
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Electrochemically enabled synthesis of substituted isoxazolines
Creator:
Holman, Samuel David Lee
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The design, synthesis and optimisation of αvβ6 antagonists as potential idiopathic pulmonary fibrosis agents
Creator:
Anderson, Niall A.
Date:
2013
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The use of structure-based drug design to optimise protein-ligand interactions
Creator:
Bertrand, Sophie
Date:
2015
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
Physicochemical studies on spectroscopic characterization, preconcentration, separation, determination and/or chemical speciation of various inorganic and organic complex species in different media
Creator:
El-Shahawi, Mohammad S.
Date:
2013
Department, School or Faculty:
Department of Pure and Applied Chemistry
Investigating novel reagents in organic synthesis
Creator:
Dimitrova, Daniela
Date:
2022
Funder:
Engineering and Physical Sciences Research Council
and
GlaxoSmithKline foundation
Department, School or Faculty:
Department of Pure and Applied Chemistry
Synthesis enabled drug discovery
Creator:
Hassell-Hart, Storm James
Date:
2017
Funder:
GlaxoSmithKline foundation
Department, School or Faculty:
Department of Pure and Applied Chemistry
The development and evaluation of a method for the quantitative determination of a monoclonal antibody using capillary electrophoresis-high resolution mass spectrometry
Creator:
Snell, Richard
Date:
2020
Funder:
GlaxoSmithKline
Department, School or Faculty:
Department of Pure and Applied Chemistry
The search for radicals in unexpected places
Creator:
Clark, Kenneth Forbes
Date:
2022
Funder:
AstraZeneca
Department, School or Faculty:
Department of Pure and Applied Chemistry
Novel methods to access tracelessly labelled molecules via iridium-catalysed hydrogen isotope exchange
Creator:
Townsley, J. Conor
Date:
2022
Department, School or Faculty:
Department of Pure and Applied Chemistry
Human bioaccessibility of potentially toxic elements in soils using three in-vitro extraction methods
Creator:
Al-Wahaibi, Bushra Salim
Date:
2012
Funder:
Sultan Qaboos University
Department, School or Faculty:
Department of Pure and Applied Chemistry
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